Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
| ▸ | MMP9 | P14780 | 1/20 | 0.59 |
| ▸ | MMP8 | P22894 | 1/20 | 0.59 |
| ▸ | MMP13 | P45452 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12570935 | 0.92 | POLB (0.71) | POLBALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL4594909 | 0.88 | POLB (0.79) | POLBALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL4066416 | 0.87 | POLB (0.77) | POLBALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL7160320 | 0.87 | POLB (0.77) | POLBALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL12912609 | 0.87 | POLB (0.77) | POLBALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL9775630 | 0.85 | POLB (0.75) | POLBALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL9614881 | 0.84 | POLB (0.84) | POLBALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL12891515 | 0.84 | POLB (0.73) | POLBALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL17670526 | 0.84 | POLB (0.77) | POLBALDH1A1KMT2AMEN1NPSR1 | |
| SCHEMBL16180691 | 0.83 | POLB (0.82) | POLBALDH1A1KMT2AMEN1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801582-A | Novel dihydro pteridinone derivative, preparing method thereof and application to medicine | 合肥工业大学 | 2016-07-27 | — | — | CN | disclosed |