Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.64 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 7/20 | 0.63 |
| ▸ | TP53 | P04637 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 3/20 | 0.61 |
| ▸ | CA2 | P00918 | 3/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | MMP1 | P03956 | 1/20 | 0.59 |
| ▸ | MMP2 | P08253 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4066416 | 0.95 | POLB (0.77) | POLBKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL9775630 | 0.94 | POLB (0.75) | POLBKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL11247690 | 0.92 | POLB (0.68) | POLBKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL9614881 | 0.91 | POLB (0.84) | POLBKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL28079515 | 0.88 | POLB (0.79) | POLBKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL12912609 | 0.87 | POLB (0.77) | POLBKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL7160320 | 0.87 | POLB (0.77) | POLBKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL396728 | 0.86 | POLB (0.58) | POLBKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL12891515 | 0.84 | POLB (0.73) | POLBKMT2AMEN1ALDH1A1NPSR1 | |
| SCHEMBL19262185 | 0.84 | LMNA (0.63) | POLBKMT2AMEN1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8476456-B2 | Process for the preparation of 4-(imidazol-1-yl)benzenesulfonamide derivatives | PALAU PHARMA, S.A. (ES) | 2013-07-02 | — | — | US | disclosed |
| EP-1873200-A1 | An improved process for making an external plasticization of aliphatic polyamides and plasticizers useful for said plasticization | Arkema France (FR) | 2008-01-02 | — | — | EP | disclosed |