Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.62 |
| ▸ | APOBEC3G | Q9HC16 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.48 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13575620 | 0.90 | HPGD (0.51) | HPGDRAB9ASMN1; SMN2APOBEC3GALDH1A1 | |
| SCHEMBL13575616 | 0.90 | BRD4 (0.53) | HPGDRAB9ASMN1; SMN2APOBEC3GALDH1A1 | |
| SCHEMBL8392994 | 0.90 | RAB9A (0.62) | HPGDRAB9ASMN1; SMN2APOBEC3GALDH1A1 | |
| SCHEMBL4049573 | 0.89 | SSTR4 (0.51) | HPGDRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3541556 | 0.88 | RAB9A (0.49) | HPGDRAB9ASMN1; SMN2APOBEC3GALDH1A1 | |
| SCHEMBL13575476 | 0.88 | SSTR5 (0.55) | HPGDRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL3541559 | 0.88 | RAB9A (0.49) | HPGDRAB9ASMN1; SMN2APOBEC3GALDH1A1 | |
| SCHEMBL13175554 | 0.86 | HRH3 (0.55) | HPGDRAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL12825174 | 0.85 | KMT2A (0.57) | HPGDRAB9ASMN1; SMN2ALDH1A1ALOX12 | |
| SCHEMBL3537704 | 0.85 | SSTR5 (0.47) | HPGDRAB9ASMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105801582-A | Novel dihydro pteridinone derivative, preparing method thereof and application to medicine | 合肥工业大学 | 2016-07-27 | — | — | CN | disclosed |