SCHEMBL28079646

SCHEMBL28079646

CN1C(c2ccccc2)CCCC1(C)C=O

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CHRNB2 P17787 1/20 0.46
CHRNB4 P30926 1/20 0.46
CHRNA3 P32297 1/20 0.46
CHRNA7 P36544 1/20 0.46
CHRNA4 P43681 1/20 0.46
TRPA1 O75762 1/20 0.39
RIPK1 Q13546 1/20 0.38
ALDH1A1 P00352 2/20 0.37
ATM Q13315 1/20 0.37
MAOA P21397 1/20 0.36
MAOB P27338 1/20 0.36
HSD11B1 P28845 1/20 0.35
BRD4 O60885 3/20 0.34
TSHR P16473 1/20 0.34
KMT2A Q03164 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL439204 0.71 CHRNB2 (0.47) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL439205 0.68 CHRNB2 (0.47) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL27657845 0.67 CHRNB2 (0.50) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL27570298 0.66 CHRNB2 (0.44) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
Water SCHEMBL28326091 0.65 CHRNB2 (0.43) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL155935 0.64 CHRNB2 (1.00) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL13238778 0.64 CHRNB2 (1.00) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL15836592 0.64 CHRNB2 (1.00) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL13330544 0.64 CHRNB2 (0.55) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4
SCHEMBL441197 0.64 CHRNB2 (0.42) CHRNB2CHRNB4CHRNA3CHRNA7CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793239-A UV ABSORBING COMPOUNDS, COMPOSITIONS COMPRISING SAME AND USES THEREOF 珊瑚防晒私人有限公司 2016-07-20 CN disclosed