Formic Acid Methyl Ester

Formic Acid Methyl Ester

SCHEMBL28079722

CC(C)Cc1cccc(OCc2ccccc2)c1.COC=O

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAOB P27338 5/20 0.55
MAOA P21397 1/20 0.55
BCHE P06276 8/20 0.52
CCNB2 O95067 1/20 0.50
CDK1 P06493 1/20 0.50
CDK4 P11802 1/20 0.50
CCNB1 P14635 1/20 0.50
CCND1 P24385 1/20 0.50
CCNB3 Q8WWL7 1/20 0.50
CYP4F2 P78329 1/20 0.49
CYP4A11 Q02928 1/20 0.49
MME P08473 1/20 0.48
ACE P12821 1/20 0.48
CPA1 P15085 1/20 0.48
ACE2 Q9BYF1 1/20 0.48
PTGES O14684 1/20 0.48
NR4A2 P43354 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL321092 0.90 MAOB (0.62) MAOBMAOABCHECYP4F2CYP4A11
SCHEMBL25480447 0.81 MAOB (0.63) MAOBMAOABCHECYP4F2CYP4A11
Isobutylbenzene SCHEMBL27821325 0.80 TAAR1 (0.52) MAOA
SCHEMBL2747426 0.79 TAAR1 (0.65) MAOBMAOABCHECYP4F2CYP4A11
SCHEMBL30211131 0.79 TAAR1 (0.65) MAOBMAOABCHECYP4F2CYP4A11
SCHEMBL21583868 0.79 TAAR1 (0.65) MAOBMAOABCHECYP4F2CYP4A11
SCHEMBL2747423 0.79 TAAR1 (0.65) MAOBMAOABCHECYP4F2CYP4A11
SCHEMBL2290856 0.78 MAOA (0.46) MAOBMAOABCHECCNB2CDK1
SCHEMBL17386027 0.78 CYP4F2 (0.59) MAOBBCHECYP4F2CYP4A11MME
SCHEMBL6624802 0.78 CYP4F2 (0.59) MAOBBCHECYP4F2CYP4A11MME

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106279283-A Novel activators of glucokinase 症变治疗公司 2017-01-04 CN disclosed
CN-101821276-B Novel glucokinase activators 症变治疗公司 2016-08-31 CN disclosed