Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | GAA | P10253 | 1/20 | 0.69 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.66 |
| ▸ | CES1 | P23141 | 2/20 | 0.66 |
| ▸ | CES2 | O00748 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | NOS1 | P29475 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA2 | P00918 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Urea SCHEMBL27562006 | 0.93 | MAPK1 (0.74) | MAPK1POLBLMNAGAASRD5A2 | |
| Carbamic Acid SCHEMBL27688398 | 0.93 | MAPK1 (0.74) | MAPK1POLBLMNAGAASRD5A2 | |
| Acetone SCHEMBL27736525 | 0.93 | MAPK1 (0.74) | MAPK1POLBLMNAGAASRD5A2 | |
| Acetic Acid SCHEMBL27610374 | 0.93 | MAPK1 (0.74) | MAPK1POLBLMNAGAASRD5A2 | |
| Methylamine SCHEMBL27262212 | 0.93 | MAPK1 (0.74) | MAPK1POLBLMNAGAASRD5A2 | |
| Methylamine SCHEMBL27784987 | 0.91 | MAPK1 (0.72) | MAPK1POLBLMNAGAASRD5A2 | |
| Ethane SCHEMBL28237274 | 0.91 | MAPK1 (0.77) | MAPK1POLBLMNAGAASRD5A2 | |
| Hydroxyamine SCHEMBL28061871 | 0.91 | MAPK1 (0.77) | MAPK1POLBLMNAGAASRD5A2 | |
| Hydrazine SCHEMBL27600926 | 0.91 | MAPK1 (0.77) | MAPK1POLBLMNAGAASRD5A2 | |
| SCHEMBL229627 | 0.91 | POLB (0.82) | MAPK1POLBLMNAGAASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109988094-A | A kind of preparation method of ethanesulfonic acid Nintedanib | 石药集团中奇制药技术（石家庄）有限公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-109879784-A | A kind of diphenyl amine compound and its application | 中国科学院广州生物医药与健康研究院 | 2019-06-14 | — | — | CN | disclosed |
| CN-105272904-B | N- phenylamide compound and its application | 中国科学院广州生物医药与健康研究院 | 2019-04-09 | — | — | CN | disclosed |
| CN-108727307-A | Compound and its application method | 安吉奥斯医药品有限公司 | 2018-11-02 | — | — | CN | disclosed |
| CN-104936954-B | Compounds and methods of use thereof | 安吉奥斯医药品有限公司 | 2018-08-14 | — | — | CN | disclosed |
| CN-108276323-A | N (O, S)-miscellaneous indene derivative of a kind of 3- function dough and its application in anti respiratory syncytial virus | 北京交通大学 | 2018-07-13 | — | — | CN | disclosed |
| CN-105683155-A | Novel diamine, polyamic acid, and polyimide | 日产化学工业株式会社 | 2016-06-15 | — | — | CN | disclosed |