SCHEMBL28079852

SCHEMBL28079852

[CH2]c1ccc(N(Cc2ccccc2)Cc2ccccc2)cc1C

nearest known ligand 0.58

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.58
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46
TSHR P16473 2/20 0.46
NR1H2 P55055 2/20 0.44
NR1H3 Q13133 2/20 0.44
S1PR1 P21453 4/20 0.43
NR3C1 P04150 1/20 0.43
CNR2 P34972 1/20 0.42
SLC16A3 O15427 1/20 0.40
SLC16A1 P53985 1/20 0.40
ALDH1A1 P00352 1/20 0.39
QPCT Q16769 1/20 0.39
PTPN1 P18031 1/20 0.39
BCL2L1 Q07817 1/20 0.39
MCL1 Q07820 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10781342 0.79 CYP2C19 (0.58) CYP2C19CRHBPCRHR2TSHRNR1H2
SCHEMBL6013668 0.77 CYP2C19 (0.54) CYP2C19CRHBPCRHR2TSHRNR1H2
SCHEMBL10779688 0.77 CYP2C19 (0.54) CYP2C19CRHBPCRHR2TSHRNR1H2
SCHEMBL10779813 0.77 CYP2C19 (0.54) CYP2C19CRHBPCRHR2TSHRNR1H2
SCHEMBL9629634 0.77 CYP2C19 (0.54) CYP2C19CRHBPCRHR2TSHRNR1H2
SCHEMBL19827216 0.76 CYP2C19 (0.50) CYP2C19CRHBPCRHR2TSHRNR1H2
SCHEMBL12679044 0.76 CYP2C19 (0.50) CYP2C19CRHBPCRHR2TSHRNR1H2
SCHEMBL13779235 0.76 CYP2C19 (0.53) CYP2C19CRHBPCRHR2TSHRNR1H2
SCHEMBL1199323 0.76 CYP2C19 (0.53) CYP2C19CRHBPCRHR2TSHRNR1H2
SCHEMBL10781440 0.76 CYP2C19 (0.53) CYP2C19CRHBPCRHR2TSHRNR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105793779-A Molecular glass mixtures for organic electronics applications 分子玻璃公司 2016-07-20 CN disclosed