Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.49 |
| ▸ | SLC16A1 | P53985 | 1/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.46 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CRHBP | P24387 | 1/20 | 0.44 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703353 | 0.83 | HTT (0.56) | CYP2C19SLC16A3SLC16A1NR3C1GAA | |
| SCHEMBL11544567 | 0.79 | TSHR (0.59) | SLC16A3SLC16A1MAPTKDM4ETSHR | |
| SCHEMBL30394165 | 0.79 | SLC16A3 (0.54) | CYP2C19SLC16A3SLC16A1TAS2R14GAA | |
| SCHEMBL26104957 | 0.79 | SLC16A3 (0.54) | CYP2C19SLC16A3SLC16A1TAS2R14GAA | |
| SCHEMBL26105961 | 0.77 | SLC16A3 (0.52) | CYP2C19SLC16A3SLC16A1MAPTCRHBP | |
| SCHEMBL30394561 | 0.77 | SLC16A3 (0.52) | CYP2C19SLC16A3SLC16A1MAPTCRHBP | |
| SCHEMBL28079852 | 0.77 | CYP2C19 (0.58) | CYP2C19SLC16A3SLC16A1NR3C1CRHBP | |
| SCHEMBL10781342 | 0.77 | CYP2C19 (0.58) | CYP2C19NR3C1CRHBPCRHR2TSHR | |
| SCHEMBL10781554 | 0.76 | SLC16A3 (0.48) | CYP2C19SLC16A3SLC16A1GAAMAPT | |
| SCHEMBL10949296 | 0.76 | SLC16A3 (0.57) | CYP2C19SLC16A3SLC16A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166350-A | Process for the manufacture of fluoran compounds | CIBA-GEIGY CORPORATION (US) | 1992-11-24 | — | — | US | disclosed |