Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | SCN4A | P35499 | 2/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL9844917 | 0.92 | LMNA (0.48) | LMNASLC6A4POLBMEN1KMT2A | |
| SCHEMBL43945 | 0.89 | SLC6A4 (0.56) | LMNASLC6A4SCN4A | |
| Benzene SCHEMBL28170835 | 0.89 | SLC6A4 (0.56) | LMNASLC6A4SCN4A | |
| SCHEMBL176808 | 0.89 | SLC6A4 (0.56) | LMNASLC6A4SCN4A | |
| SCHEMBL170928 | 0.89 | SLC6A4 (0.56) | LMNASLC6A4SCN4A | |
| SCHEMBL29503095 | 0.89 | SLC6A4 (0.56) | LMNASLC6A4SCN4A | |
| Hydrochloric Acid SCHEMBL5945406 | 0.87 | SLC6A4 (0.54) | LMNASLC6A4SCN4A | |
| Hydrochloric Acid SCHEMBL7185884 | 0.87 | SLC6A4 (0.54) | LMNASLC6A4SCN4A | |
| Iodide SCHEMBL6672339 | 0.87 | SLC6A4 (0.54) | LMNASLC6A4SCN4A | |
| SCHEMBL28382272 | 0.87 | SLC6A4 (0.54) | LMNASLC6A4SCN4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105777706-A | 3-[(benzo[d][1,3]dioxolane-4-yl)-oxy]-3-arylpropylamine compound and application thereof | 江苏恩华药业股份有限公司 | 2016-07-20 | — | — | CN | disclosed |