2,4-Dihydroxybenzoic Acid

2,4-Dihydroxybenzoic Acid

SCHEMBL28080

O=C(O)c1ccc(O)cc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 6/20 1.00
CA1 P00915 6/20 1.00
CA2 P00918 6/20 1.00
CA7 P43166 6/20 1.00
CA9 Q16790 6/20 1.00
CA14 Q9ULX7 6/20 1.00
ALDH1A1 P00352 6/20 1.00
TSHR P16473 1/20 1.00
CES2 O00748 1/20 0.70
ALOX5 P09917 1/20 0.67
PTGS2 P35354 1/20 0.67
KDM4E B2RXH2 4/20 0.61
MAPT P10636 2/20 0.61
GAA P10253 2/20 0.61
ESR2 Q92731 2/20 0.61
CYP3A4 P08684 1/20 0.61
PTPN1 P18031 1/20 0.61
MEN1 O00255 1/20 0.61
USP2 O75604 1/20 0.61
KMT2A Q03164 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2,4-Dihydroxybenzoic Acid SCHEMBL29573604 1.00 CA12 (1.00) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL28285004 1.00 CA12 (1.00) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL8603122 0.98 ALDH1A1 (0.95) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL8201193 0.98 ALDH1A1 (0.95) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL11146347 0.98 ALDH1A1 (0.95) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL8906720 0.98 ALDH1A1 (0.95) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL8920707 0.98 ALDH1A1 (0.95) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL1198473 0.98 ALDH1A1 (0.95) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL3408180 0.98 ALDH1A1 (0.95) CA12CA1CA2CA7CA9
2,4-Dihydroxybenzoic Acid SCHEMBL8603120 0.98 ALDH1A1 (0.95) CA12CA1CA2CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 12174 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117580463-B Taste improving agent GIVAUDAN S.A. (CH) 2026-05-26 CN claimed
CN-122079764-A Method for synthesizing 4-methoxy potassium salicylate based on supermolecule assisted methylation 2026-05-26 CN claimed
CN-122057253-A 2, 4-Dihydroxybenzoic acid dissolves recrystallization equipment 天津市职业大学 2026-05-19 CN claimed
CN-122036758-A Halogen-free and phosphorus-free intrinsic flame-retardant tetrafunctional benzoxazine monomer, nitrogen-rich resin, preparation method and application thereof 淮北绿洲新材料有限责任公司 2026-05-15 CN claimed
EP-3383177-B1 COMPOSITION FOR CROP CARE AND PROTECTION ALPHA BIOPESTICIDES LTD (GB) 2026-04-22 EP claimed
EP-3495073-B2 LOW EMISSION COLD CURING BINDERS FOR FOUNDRY INDUSTRY HUETTENES ALBERTUS CHEMISCHE WERKE GMBH (DE) 2026-04-01 EP claimed
US-12559646-B2 Aqueous coating composition containing an epoxy-amine system and an aromatic carboxylic acid as curing catalyst BASF COATINGS GMBH (DE) 2026-02-24 US claimed
EP-4687488-A1 SWEETNESS AND TASTE IMPROVEMENT OF NON-SUCROSE SWEETENERS WITH HYDROXYBENZOIC ACID The Coca-Cola Company (US) 2026-02-11 EP claimed
US-20260002924-A1 METHOD FOR SELECTING ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS FROM MIXTURE OF ESTER FUNCTIONAL GROUP-CONTAINING POLYMERS AND OTHER TYPES OF POLYMERS KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2026-01-01 US claimed
EP-4665809-A1 CHEMICAL MECHANICAL PLANARIZATION FOR SHALLOW TRENCH ISOLATION Versum Materials US, LLC (US) 2025-12-24 EP claimed
US-4159208-A REACTING ALKALI METAL SALT OF AN AROMATIC CARBOXYLIC ACID AND A METAL SALT IN THE PRESENCE OF CLAY AND ALUMINUM COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1979-06-26 US claimed
US-4150108-A STEROID ENTRAPPED IN COPOLYMER MATRIX FROM A BIS(DIHYDROPYRAN) GRAHAM NEIL B 1979-04-17 US claimed
US-4141774-A METHOXYMETHYLATED NYLON TERPOLYMER DAICEL LTD. (JP) 1979-02-27 US claimed
US-4104137-A Alloy plating M&T CHEMICALS INC. (US) 1978-08-01 US claimed
US-4061810-A HYDROXYCARBOXYLIC ACID AND TIN, ANTIMONY, ALUMINUM OR ZINC HYDROXIDE OR OXIDE ALLIED CHEMICAL CORPORATION (US) 1977-12-06 US claimed
US-4036707-A ETCHING, ACTIVATING, SENSITIZING, IMMERSING IN ACCELERATOR BATH, ELECTROLESS PLATING OF NICKEL THEN COPPER SIEMENS AKTIENGESELLSCHAFT (DT) 1977-07-19 US claimed
US-3997705-A Method of coagulating a fluoro-elastomer from an aqueous dispersion thereof DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1976-12-14 US claimed
US-3965033-A Process for the production of oil-containing microcapsules FUJI PHOTO FILM CO., LTD. (JA) 1976-06-22 US claimed
US-3936451-A Process for producing salts of hexamethylenetetramine UNITED STATES PIPE AND FOUNDRY COMPANY (US) 1976-02-03 US claimed
US-3932340-A ACID CATALYSTS DAICEL LTD. (JA) 1976-01-13 US claimed