⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL555929 | 0.74 | — | — | |
| SCHEMBL29119256 | 0.74 | — | — | |
| SCHEMBL5175685 | 0.73 | — | — | |
| SCHEMBL29119091 | 0.71 | F7 (0.34) | — | |
| SCHEMBL28651841 | 0.70 | — | — | |
| SCHEMBL14659137 | 0.69 | — | — | |
| SCHEMBL1446648 | 0.69 | — | — | |
| SCHEMBL5303308 | 0.69 | MEN1 (0.40) | — | |
| SCHEMBL29119186 | 0.69 | FAAH (0.40) | — | |
| SCHEMBL28859222 | 0.69 | FAAH (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107108672-B | Condensed five rings imdazole derivatives | UCB生物制药私人有限公司 | 2019-11-08 | — | — | CN | disclosed |
| CN-109219608-A | FUSED PENTACYCLIC IMIDAZOLE DERIVATIVES AS MODULATORS OF TNF ACTIVITY | UCB生物制药私人有限公司 | 2019-01-15 | — | — | CN | disclosed |
| CN-105814048-B | Fused tricyclic benzimidizole derivatives as TNF active regulators | UCB生物制药私人有限公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-107108672-A | The five rings imdazole derivatives of fusion | UCB生物制药私人有限公司 | 2017-08-29 | — | — | CN | disclosed |
| CN-105814048-A | Fused tricyclic imidazole derivatives as modulators of TNF activity | UCB生物制药私人有限公司 | 2016-07-27 | — | — | CN | disclosed |