Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 2/20 | 0.30 |
| ▸ | CNR1 | P21554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27996460 | 1.00 | FKBP1A (0.35) | FKBP1AALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL28092128 | 1.00 | FKBP1A (0.35) | FKBP1AALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL28870856 | 0.95 | POLB (0.32) | FKBP1ASMN1; SMN2POLB | |
| SCHEMBL28284120 | 0.95 | POLB (0.32) | FKBP1ASMN1; SMN2POLB | |
| SCHEMBL27689894 | 0.87 | FKBP1A (0.35) | FKBP1AALDH1A1POLBCNR2CNR1 | |
| SCHEMBL27801798 | 0.84 | FKBP1A (0.35) | FKBP1AALDH1A1MAPTSMN1; SMN2POLB | |
| SCHEMBL27649009 | 0.83 | FKBP1A (0.34) | FKBP1AALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL27382573 | 0.82 | FKBP1A (0.48) | FKBP1AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28159943 | 0.80 | SMN1; SMN2 (0.36) | FKBP1AALDH1A1SMN1; SMN2POLB | |
| SCHEMBL28021961 | 0.78 | HSD17B10 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967066-B | Novel ss-lactam enzyme inhibitor and preparation method thereof | 明治制果药业株式会社 | 2019-07-30 | — | — | CN | disclosed |
| CN-105859609-B | Beta-lactamase inhibitor and preparation method thereof | 明治制果药业株式会社 | 2019-04-09 | — | — | CN | disclosed |
| CN-105859609-A | Beta-lactamase inhibitor and process for preparing the same | 明治制果药业株式会社 | 2016-08-17 | — | — | CN | disclosed |