Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 4/20 | 0.65 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.65 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.65 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.65 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27766401 | 0.86 | CHRNB2 (0.65) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL28190151 | 0.84 | CHRNB2 (0.63) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL11176275 | 0.84 | CHRNB2 (0.63) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL8761336 | 0.83 | CHRNB2 (0.61) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL442790 | 0.81 | CHRNB2 (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| Benzene SCHEMBL1720409 | 0.81 | CHRNB2 (0.59) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL11349063 | 0.81 | CHRNB2 (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL9142092 | 0.81 | CHRNB2 (0.60) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL13393309 | 0.80 | CHRNB2 (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A | |
| SCHEMBL5006624 | 0.80 | CHRNB2 (0.58) | CHRNB2CHRNB4CHRNA3CHRNA4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106967066-B | Novel ss-lactam enzyme inhibitor and preparation method thereof | 明治制果药业株式会社 | 2019-07-30 | — | — | CN | disclosed |
| CN-105859609-B | Beta-lactamase inhibitor and preparation method thereof | 明治制果药业株式会社 | 2019-04-09 | — | — | CN | disclosed |
| CN-106967066-A | New beta lactamase restrainer and preparation method thereof | 明治制果药业株式会社 | 2017-07-21 | — | — | CN | disclosed |
| CN-104334559-B | Beta-lactamase inhibitor and preparation method thereof | 明治制果药业株式会社 | 2017-03-22 | — | — | CN | disclosed |
| CN-105859609-A | Beta-lactamase inhibitor and process for preparing the same | 明治制果药业株式会社 | 2016-08-17 | — | — | CN | disclosed |