SCHEMBL28080748

SCHEMBL28080748

O=C=Nc1cccc(SS)c1

nearest known ligand 0.41

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
CYP3A4 P08684 3/20 0.39
TRPA1 O75762 1/20 0.39
TSHR P16473 1/20 0.35
GABRA1 P14867 1/20 0.33
GABRB2 P47870 1/20 0.33
CYP1A2 P05177 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9315146 0.84 MAPK1 (0.44) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL8937136 0.84 MAPK1 (0.44) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL31134964 0.84 MAPK1 (0.44) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL125319 0.81 CYP3A4 (0.43) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL29638353 0.81 CYP3A4 (0.43) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL28087260 0.79 MAPK1 (0.40) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL27873 0.79 TDP1 (0.54) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL10615043 0.79 TDP1 (0.54) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL11303252 0.78 MAPK1 (0.43) MAPK1TDP1CYP3A4TRPA1TSHR
SCHEMBL27621561 0.77 TDP1 (0.52) MAPK1TDP1CYP3A4TRPA1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104011103-B Polymerisable compound, its optical goods obtained and the method producing described optical goods 三井化学株式会社 2016-08-24 CN disclosed
CN-105793737-A Polymerizable composition for optical materials 三井化学株式会社 2016-07-20 CN disclosed