Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 4/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29638353 | 1.00 | CYP3A4 (0.43) | CYP3A4TRPA1MAPK1TDP1MEN1 | |
| SCHEMBL8937136 | 0.84 | MAPK1 (0.44) | CYP3A4TRPA1MAPK1TDP1POLB | |
| SCHEMBL9315146 | 0.84 | MAPK1 (0.44) | CYP3A4TRPA1MAPK1TDP1MAPT | |
| SCHEMBL31134964 | 0.84 | MAPK1 (0.44) | CYP3A4TRPA1MAPK1TDP1POLB | |
| SCHEMBL1457560 | 0.81 | MIF (0.48) | CYP3A4MAPK1TDP1MEN1KMT2A | |
| SCHEMBL28080748 | 0.81 | MAPK1 (0.41) | CYP3A4TRPA1MAPK1TDP1GABRA1 | |
| SCHEMBL2651634 | 0.80 | GABRA1 (0.42) | CYP3A4TRPA1MAPK1TDP1GABRA1 | |
| SCHEMBL7529742 | 0.80 | CYP4F2 (0.42) | TDP1KMT2AMAPTTP53POLB | |
| SCHEMBL11718768 | 0.79 | CYP3A4 (0.46) | CYP3A4TRPA1MAPK1TDP1MEN1 | |
| SCHEMBL28087260 | 0.79 | MAPK1 (0.40) | CYP3A4TRPA1MAPK1TDP1GABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 558 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12509419-B2 | Process for the distillation of isocyanates | COVESTRO DEUTSCHLAND AG (DE) | 2025-12-30 | — | — | US | claimed |
| US-20220380303-A1 | PROCESS FOR THE DISTILLATION OF ISOCYANATES | COVESTRO DEUTSCHLAND AG (DE) | 2022-12-01 | — | — | US | claimed |
| EP-4038049-A1 | PROCESS FOR THE DISTILLATION OF ISOCYANATES | Covestro Intellectual Property GmbH & Co. KG (DE) | 2022-08-10 | — | — | EP | claimed |
| CN-114423736-A | Method for distilling isocyanates | 科思创知识产权两合公司 | 2022-04-29 | — | — | CN | claimed |
| WO-2021063760-A1 | PROCESS FOR THE DISTILLATION OF ISOCYANATES | COVESTRO INTELLECTUAL PROPERTY GMBH & CO. KG (DE) | 2021-04-08 | — | — | WO | claimed |
| EP-3798208-A1 | METHOD FOR DISTILLATION OF ISOCYANATES | Covestro Deutschland AG (DE) | 2021-03-31 | — | — | EP | claimed |
| EP-1754705-A2 | Antagonists for treatment of CD11/CD18 adhesion receptor mediated disorders | Genentech, Inc. (US) | 2007-02-21 | — | — | EP | claimed |
| EP-1377589-B1 | OXAZOLYL-PYRAZOLE DERIVATIVES AS KINASE INHIBITORS | PHARMACIA ITALIA SPA (IT) | 2005-09-07 | — | — | EP | claimed |
| US-12509419-B2 | Process for the distillation of isocyanates | COVESTRO DEUTSCHLAND AG (DE) | 2025-12-30 | — | — | US | disclosed |
| US-12406696-B2 | Photopolymer compositions for thermostable photopolymers in the visible spectral range | COVESTRO DEUTSCHLAND AG (DE) | 2025-09-02 | — | — | US | disclosed |
| US-20250182787-A1 | Photopolymer Compositions for Thermostable Photopolymers in the Visible Spectral Range | COVESTRO DEUTSCHLAND AG (DE) | 2025-06-05 | — | — | US | disclosed |
| US-20250171648-A1 | Thermostable Photopolymers in the Visible Spectral Range and Photopolymer Compositions Containing Same | COVESTRO DEUTSCHLAND AG (DE) | 2025-05-29 | — | — | US | disclosed |
| US-20250155845-A1 | Triarylalkyl Borate Salts as Coinitiators in NIR Photopolymer Compositions | COVESTRO DEUTSCHLAND AG (DE) | 2025-05-15 | — | — | US | disclosed |
| CN-114423736-B | Method for distilling isocyanates | 科思创德国股份有限公司 | 2025-02-18 | — | — | CN | disclosed |
| US-4663341-A | Insecticidal n-aryl-3-aryl-4,5-dihydro-1h-pyrazole-1-carboxamides | ROHM AND HAAS COMPANY (US) | 1987-05-05 | — | — | US | disclosed |
| EP-0153127-A2 | N-aryl-3-aryl-4,5-dihydro-1H-pyrazole-1-carboxamides, processes for their production, insecticidal compositions containing them and methods for combatting insects | ROHM AND HAAS COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| US-4514210-A | Herbicidally active methyl-substituted tetrahydro-2-pyrimidinone derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-04-30 | — | — | US | disclosed |
| EP-0086411-A2 | Methyl-substituted tetrahydro-2-pyrimidinone derivatives, process for their preparation and their use as herbicides, as well as intermediates for their preparation | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-08-24 | — | — | EP | disclosed |
| US-4046909-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1977-09-06 | — | — | US | disclosed |
| US-3998958-A | Pyrrolidylidene, piperidylidene and hexahydroazepinylidene ureas as CNS depressants | MCNEIL LABORATORIES, INCORPORATED (US) | 1976-12-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12509419-B2 | Process for the distillation of isocyanates | ACMSD, MRPL9, CA9 | CYP3A4 2868/4885TRPA1 2214/4885MAPK1 3741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.