Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.51 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CLK1 | P49759 | 1/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.39 |
| ▸ | P4HB | P07237 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | VNN1 | O95497 | 3/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16502093 | 0.82 | GSK3B (0.53) | GSK3BENPP2CLK4GRM5TSHR | |
| SCHEMBL28080976 | 0.80 | GSK3B (0.61) | GSK3BENPP2CLK4GRM5CLK1 | |
| SCHEMBL14508038 | 0.80 | GSK3B (0.51) | GSK3BENPP2CLK4GRM5TSHR | |
| SCHEMBL3348656 | 0.80 | GSK3B (0.51) | GSK3BENPP2CLK4GRM5TSHR | |
| SCHEMBL15585969 | 0.80 | GSK3B (0.56) | GSK3BENPP2CLK4GRM5TSHR | |
| SCHEMBL4699585 | 0.79 | GSK3B (0.47) | GSK3BENPP2CLK4GRM5CLK1 | |
| SCHEMBL4083136 | 0.79 | GSK3B (0.58) | GSK3BENPP2CLK4GRM5TSHR | |
| SCHEMBL20494918 | 0.78 | TDP1 (0.40) | — | |
| SCHEMBL1187531 | 0.77 | GSK3B (0.49) | GSK3BENPP2CLK4GRM5TSHR | |
| SCHEMBL2500188 | 0.76 | GSK3B (0.61) | GSK3BENPP2CLK4GRM5CLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710420-B | Azabicyclic formula compound or its salt, containing its medicine, compositions and application | 大鹏药品工业株式会社 | 2016-07-27 | — | — | CN | disclosed |