Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 2/20 | 0.61 |
| ▸ | GRM5 | P41594 | 1/20 | 0.48 |
| ▸ | CLK1 | P49759 | 1/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.46 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.46 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.46 |
| ▸ | P4HB | P07237 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.45 |
| ▸ | VNN1 | O95497 | 3/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60691 | 0.82 | GSK3B (0.62) | GSK3BGRM5 | |
| SCHEMBL102642 | 0.82 | GSK3B (0.41) | GSK3BGRM5 | |
| SCHEMBL2164429 | 0.82 | GSK3B (0.62) | GSK3BGRM5CLK1DYRK1ADYRK1B | |
| SCHEMBL29441888 | 0.82 | GSK3B (0.62) | GSK3BGRM5 | |
| SCHEMBL23079142 | 0.80 | GSK3B (0.61) | GSK3BGRM5CLK1DYRK1ADYRK1B | |
| SCHEMBL39137 | 0.80 | GSK3B (0.61) | GSK3BGRM5CLK1DYRK1ADYRK1B | |
| Hydrochloric Acid SCHEMBL2031438 | 0.80 | GSK3B (0.61) | GSK3BGRM5 | |
| SCHEMBL4169583 | 0.80 | GSK3B (0.61) | GSK3BGRM5CLK1DYRK1ADYRK1B | |
| SCHEMBL2500188 | 0.80 | GSK3B (0.61) | GSK3BGRM5CLK1DYRK1ADYRK1B | |
| SCHEMBL11706688 | 0.80 | GSK3B (0.61) | GSK3BGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104710420-B | Azabicyclic formula compound or its salt, containing its medicine, compositions and application | 大鹏药品工业株式会社 | 2016-07-27 | — | — | CN | disclosed |