Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL60018 | 0.97 | — | — | |
| SCHEMBL31193668 | 0.94 | — | — | |
| SCHEMBL8619333 | 0.94 | — | — | |
| SCHEMBL31094050 | 0.94 | — | — | |
| Hydrochloric Acid SCHEMBL28767127 | 0.94 | — | — | |
| SCHEMBL31193714 | 0.84 | — | — | |
| SCHEMBL31193777 | 0.84 | — | — | |
| SCHEMBL31193707 | 0.84 | — | — | |
| Pyrimidine SCHEMBL28570129 | 0.82 | CYP19A1 (0.32) | — | |
| Monoethanolamine SCHEMBL8618051 | 0.80 | ALDH1A1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793264-A | Substituted dihydrobenzofuran-piperidine-ketone derivative, preparation and use thereof | 四川海思科制药有限公司 | 2016-07-20 | — | — | CN | disclosed |