Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chlorobenzene SCHEMBL9749325 | 0.98 | TSHR (0.55) | TSHRPOLBALDH1A1KMT2AMEN1 | |
| Chlorobenzene SCHEMBL10423435 | 0.87 | TSHR (0.44) | TSHRPOLBALDH1A1KMT2AMEN1 | |
| 1,4-Dichlorobenzene SCHEMBL28264138 | 0.85 | TSHR (0.53) | TSHRPOLBALDH1A1CYP1A2MAPT | |
| Dimethylformamide SCHEMBL28224251 | 0.81 | POLB (0.55) | TSHRPOLBALDH1A1KMT2AMEN1 | |
| 1,2-Dichlorobenzene SCHEMBL28124693 | 0.80 | TSHR (0.53) | TSHRPOLBALDH1A1KMT2AMEN1 | |
| Chlorobenzene SCHEMBL27337663 | 0.79 | TSHR (0.65) | TSHRALDH1A1KMT2AMEN1CYP1A2 | |
| Chlorobenzene SCHEMBL875663 | 0.79 | TSHR (0.73) | TSHRALDH1A1KMT2AMEN1CYP1A2 | |
| Biphenyl SCHEMBL27802171 | 0.77 | ALDH1A1 (0.50) | TSHRPOLBALDH1A1KMT2AMEN1 | |
| Chlorobenzene SCHEMBL28123282 | 0.77 | TSHR (0.61) | TSHRALDH1A1KMT2AMEN1CYP1A2 | |
| Chlorobenzene SCHEMBL27348154 | 0.76 | TSHR (0.69) | TSHRALDH1A1KMT2AMEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105793387-A | Composition containing a polymeric binder comprising acrylate and/or methacrylate units | 默克专利有限公司 | 2016-07-20 | — | — | CN | disclosed |