Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | CA1 | P00915 | 1/20 | 0.62 |
| ▸ | CA2 | P00918 | 1/20 | 0.62 |
| ▸ | CA9 | Q16790 | 1/20 | 0.62 |
| ▸ | SRC | P12931 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.53 |
| ▸ | GABRP | O00591 | 1/20 | 0.53 |
| ▸ | GABRD | O14764 | 1/20 | 0.53 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.53 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.53 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.53 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.53 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.53 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28082036 | 0.88 | NPC1 (0.64) | KDM4EMEN1KMT2AMAPTHPGD | |
| SCHEMBL2760055 | 0.84 | HDAC3 (0.60) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL6019366 | 0.81 | POLB (0.64) | MEN1KMT2AMAPTLMNANHERF1 | |
| SCHEMBL28788142 | 0.81 | KDM4E (0.52) | KDM4EMAPTCYP19A1HDAC2 | |
| SCHEMBL2760003 | 0.81 | SRC (0.83) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL6245500 | 0.81 | KDM4E (0.57) | KDM4EMEN1KMT2AMAPTLMNA | |
| SCHEMBL2735969 | 0.81 | CA12 (0.72) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL1415543 | 0.81 | POLB (0.58) | KDM4EMAPTLMNAHDAC2 | |
| SCHEMBL2735829 | 0.80 | CA12 (0.68) | KDM4ECA12CA1CA2CA9 | |
| SCHEMBL14845701 | 0.80 | KDM4E (0.72) | KDM4ECA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105820104-A | Indole-2-acetamide compound with anti-inflammatory effect, and application thereof in preparation of anti-inflammatory drugs | 温州医科大学 | 2016-08-03 | — | — | CN | disclosed |