Ethylene Glycol

Ethylene Glycol

SCHEMBL28082038

C=C(C)C(=O)OCC(CC)(COC(=O)C(=C)C)COC(=O)C(=C)C.OCCO

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.44
TSHR P16473 3/20 0.43
ALDH1A1 P00352 3/20 0.38
TP53 P04637 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
HIF1A Q16665 1/20 0.33
POLB P06746 1/20 0.30
APEX1 P27695 1/20 0.30
HTT P42858 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CYP4F2 P78329 1/20 0.30
CYP4A11 Q02928 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propanol SCHEMBL9222648 0.94 TSHR (0.46) THRBTSHRALDH1A1TP53CYP3A4
Propanol SCHEMBL9226264 0.94 TSHR (0.46) THRBTSHRALDH1A1TP53CYP3A4
Propanol SCHEMBL9222638 0.94 TSHR (0.46) THRBTSHRALDH1A1TP53CYP3A4
Alcohol SCHEMBL9220453 0.94 THRB (0.46) THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL28149678 0.94 THRB (0.48) THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL23636 0.94 THRB (0.48) THRBTSHRALDH1A1TP53CYP3A4
Ethylene Glycol SCHEMBL2356475 0.93 THRB (0.42) THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL10391726 0.92 THRB (0.47) THRBTSHRALDH1A1TP53CYP3A4
Propane SCHEMBL28078056 0.92 THRB (0.47) THRBTSHRALDH1A1TP53CYP3A4
SCHEMBL5884750 0.92 THRB (0.47) THRBTSHRALDH1A1TP53CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101636469-B Comprise the liquid crystal polymer of the patternable of thio-ether units 罗利克有限公司 2016-08-17 CN disclosed