Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | AKT1 | P31749 | 1/20 | 0.40 |
| ▸ | AKT2 | P31751 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20081370 | 0.80 | PDE10A (0.61) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL8083514 | 0.79 | PDE10A (0.64) | TDP1ALDH1A1KDM4EL3MBTL1PDE10A | |
| SCHEMBL30724619 | 0.78 | DHODH (0.45) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL9953697 | 0.78 | DHODH (0.45) | ALDH1A1KDM4ELMNAKMT2AMEN1 | |
| SCHEMBL28083091 | 0.77 | TOP1 (0.51) | TDP1ALDH1A1KDM4EL3MBTL1PDE10A | |
| SCHEMBL13712729 | 0.77 | PSMB5 (0.45) | ALDH1A1HPGDKDM4ELMNANPSR1 | |
| SCHEMBL19753812 | 0.77 | DHODH (0.38) | TDP1ALDH1A1HPGDKDM4EL3MBTL1 | |
| SCHEMBL1989337 | 0.75 | TOP1 (0.46) | ALDH1A1HPGDKDM4EPDE10ALMNA | |
| SCHEMBL21973538 | 0.74 | PTGS1 (0.46) | TDP1ALDH1A1KDM4E | |
| SCHEMBL13869175 | 0.74 | PTGS1 (0.46) | TDP1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083845-A | A kind of 1,5 naphthyridine type luminous organic material compounds and synthetic method thereof and application | 金陵科技学院 | 2016-11-09 | — | — | CN | disclosed |