Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
| ▸ | AKT2 | P31751 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27653760 | 0.92 | MEN1 (0.65) | TOP1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL3702970 | 0.91 | MEN1 (0.46) | TOP1KMT2AMEN1KDM4EPKM | |
| SCHEMBL1352152 | 0.87 | MEN1 (0.43) | TOP1KMT2AMEN1KDM4EPKM | |
| SCHEMBL1349852 | 0.87 | AKT1 (0.48) | TOP1KMT2AMEN1KDM4EL3MBTL1 | |
| Quinoline SCHEMBL28117842 | 0.85 | ALDH1A1 (0.55) | TOP1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL1351892 | 0.83 | AKT1 (0.46) | TOP1KMT2AMEN1KDM4EPKM | |
| SCHEMBL30477086 | 0.81 | PSMB5 (0.54) | TOP1KMT2AMEN1KDM4EPSMB5 | |
| SCHEMBL2899383 | 0.81 | TOP1 (0.50) | TOP1KMT2AMEN1L3MBTL1ALDH1A1 | |
| SCHEMBL28280373 | 0.81 | FGFR1 (0.55) | TOP1KMT2AMEN1KDM4EGAA | |
| SCHEMBL1993651 | 0.81 | TOP1 (0.50) | TOP1KDM4EPKML3MBTL1AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083845-A | A kind of 1,5 naphthyridine type luminous organic material compounds and synthetic method thereof and application | 金陵科技学院 | 2016-11-09 | — | — | CN | disclosed |