Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 known ✓ | Q99720 | 2/20 | 0.42 |
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.39 |
| ▸ | EBP | Q15125 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL28082659 | 1.00 | SIGMAR1 (0.42) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Bromide SCHEMBL28082647 | 1.00 | SIGMAR1 (0.42) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Bromide SCHEMBL28082507 | 1.00 | SIGMAR1 (0.42) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Bromide SCHEMBL28082771 | 1.00 | SIGMAR1 (0.42) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Bromide SCHEMBL28082998 | 1.00 | SIGMAR1 (0.42) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Bromide SCHEMBL28082779 | 1.00 | SIGMAR1 (0.42) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Bromide SCHEMBL28245123 | 1.00 | SIGMAR1 (0.42) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| SCHEMBL9003672 | 0.91 | SIGMAR1 (0.48) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Iodide SCHEMBL38651193 | 0.89 | SIGMAR1 (0.47) | SIGMAR1EBPCHRM2CHRM4CHRM5 | |
| Hydrochloric Acid SCHEMBL27685587 | 0.89 | SIGMAR1 (0.47) | SIGMAR1EBPCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105814092-B | Composition for hydrophilic cured product | 三井化学株式会社 | 2018-09-21 | — | — | CN | disclosed |
| CN-107250226-A | Acrylic resin modified solidfied material and its layered product and their manufacture method | 三井化学株式会社 | 2017-10-13 | — | — | CN | disclosed |
| CN-105814092-A | Composition for hydrophilic cured product | 三井化学株式会社 | 2016-07-27 | — | — | CN | disclosed |