Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.47 |
| ▸ | CDK1 | P06493 | 2/20 | 0.47 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.47 |
| ▸ | GSK3A | P49840 | 2/20 | 0.47 |
| ▸ | GSK3B | P49841 | 2/20 | 0.47 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.47 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4867556 | 0.86 | CLK4 (0.48) | CLK4DYRK1AKMT2AMEN1KDM4E | |
| SCHEMBL6557994 | 0.81 | MAPT (0.52) | CLK4DYRK1AKMT2AMEN1KDM4E | |
| SCHEMBL30964094 | 0.79 | TLR8 (0.43) | CLK4DYRK1AKMT2AMEN1KDM4E | |
| SCHEMBL29284767 | 0.79 | TLR8 (0.43) | CLK4DYRK1AKMT2AMEN1KDM4E | |
| SCHEMBL15825831 | 0.78 | CLK4 (0.53) | CLK4KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL30484918 | 0.78 | CLK4 (0.53) | CLK4KMT2AKDM4ECYP1A2CYP3A4 | |
| SCHEMBL1823930 | 0.77 | DYRK1A (0.53) | CLK4DYRK1AKMT2AMEN1KDM4E | |
| SCHEMBL15232687 | 0.77 | DYRK1A (0.53) | CLK4DYRK1AKMT2AMEN1KDM4E | |
| SCHEMBL15884659 | 0.77 | NPC1 (0.44) | CLK4DYRK1AKMT2AMEN1KDM4E | |
| SCHEMBL8655989 | 0.77 | CCR1 (0.54) | CLK4KDM4ECYP3A4CYP2D6CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083845-A | A kind of 1,5 naphthyridine type luminous organic material compounds and synthetic method thereof and application | 金陵科技学院 | 2016-11-09 | — | — | CN | claimed |
| CN-106083845-A | A kind of 1,5 naphthyridine type luminous organic material compounds and synthetic method thereof and application | 金陵科技学院 | 2016-11-09 | — | — | CN | disclosed |