Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.47 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.47 |
| ▸ | MGMT | P16455 | 3/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.39 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 3/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 2/20 | 0.38 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.38 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.38 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | PNP | P00491 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CDK1 | P06493 | 3/20 | 0.37 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3630347 | 0.79 | GDA (0.56) | PDPK1GDAMGMTKDRAURKB | |
| SCHEMBL1934408 | 0.79 | SYK (0.51) | GDAXDHSYK | |
| SCHEMBL20508956 | 0.78 | TDP1 (0.37) | — | |
| SCHEMBL1684049 | 0.77 | GDA (0.58) | PDPK1GDAMGMTKDRAURKB | |
| SCHEMBL29509029 | 0.77 | GDA (0.58) | PDPK1GDAMGMTKDRAURKB | |
| SCHEMBL27461919 | 0.77 | GDA (0.58) | PDPK1GDAMGMTKDRAURKB | |
| SCHEMBL27157944 | 0.76 | CDK1 (0.52) | PDPK1GDAMGMTKDRAURKB | |
| SCHEMBL30107648 | 0.76 | GDA (0.56) | PDPK1GDAMGMTKDRAURKB | |
| SCHEMBL31435111 | 0.75 | GDA (0.51) | PDPK1GDAMGMTKDRAURKB | |
| Zinc Ion SCHEMBL31405446 | 0.75 | GDA (0.54) | PDPK1GDAMGMTKDRAURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117241803-A | Purine nucleosides, intermediates and methods of making the same | 阿斯特罗赛特制药公司 | 2023-12-15 | — | — | CN | disclosed |
| CN-112759595-B | Method for synthesizing chiral acyclic nucleoside by asymmetric allylation reaction | 河南师范大学 | 2023-01-20 | — | — | CN | disclosed |
| CN-114127082-A | Modified cyclic dinucleoside compounds as STING modulators | 阿里戈斯治疗公司 | 2022-03-01 | — | — | CN | disclosed |
| CN-112759595-A | Method for synthesizing chiral acyclic nucleoside by asymmetric allylation reaction | 河南师范大学 | 2021-05-07 | — | — | CN | disclosed |
| CN-109694397-A | Cyclic annular dinucleotides compound, preparation method and application | 上海弘翊生物科技有限公司 | 2019-04-30 | — | — | CN | disclosed |
| CN-105829308-A | Isochromene derivatives as phosphoinositide 3-kinase inhibitors | 奇斯药制品公司 | 2016-08-03 | — | — | CN | disclosed |