SCHEMBL3630347

SCHEMBL3630347

CC(=O)c1nc(N)c2[nH]cnc2n1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GDA Q9Y2T3 2/20 0.56
PDPK1 O15530 1/20 0.56
MGMT P16455 3/20 0.48
DPP4 P27487 1/20 0.45
PI4KA P42356 2/20 0.44
PI4K2B Q8TCG2 2/20 0.44
PI4K2A Q9BTU6 2/20 0.44
PI4KB Q9UBF8 2/20 0.44
LMNA P02545 1/20 0.44
DRD3 P35462 1/20 0.44
XDH P47989 1/20 0.44
LRRK2 Q5S007 1/20 0.44
KDR P35968 1/20 0.44
AURKB Q96GD4 1/20 0.44
PNP P00491 1/20 0.44
POLA1 P09884 1/20 0.42
MAP3K5 Q99683 1/20 0.41
CDK2 P24941 3/20 0.41
CDK1 P06493 2/20 0.41
CCNB1 P14635 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1684049 0.85 GDA (0.58) GDAPDPK1MGMTDPP4PI4KA
SCHEMBL29509029 0.85 GDA (0.58) GDAPDPK1MGMTDPP4PI4KA
SCHEMBL27461919 0.85 GDA (0.58) GDAPDPK1MGMTDPP4PI4KA
Acetic Acid SCHEMBL1903435 0.84 GDA (0.50) GDAPDPK1MGMTDPP4PI4KA
SCHEMBL30107648 0.83 GDA (0.56) GDAPDPK1MGMTDPP4PI4KA
SCHEMBL31435111 0.83 GDA (0.51) GDAPDPK1MGMTDPP4PI4KA
Zinc Ion SCHEMBL31405446 0.82 GDA (0.54) GDAPDPK1MGMTDPP4PI4KA
SCHEMBL6045492 0.81 GDA (0.53) GDAPDPK1MGMTDPP4PI4KA
SCHEMBL9393667 0.80 PDPK1 (0.49) GDAPDPK1MGMTDPP4PI4KA
SCHEMBL8506351 0.80 PDPK1 (0.51) GDAPDPK1MGMTDPP4PI4KA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119375400-A Sample pretreatment method for detecting CD38 enzyme activity in whole blood sample and method for detecting blood CD38 enzyme activity by high performance liquid chromatography 北京医院 2025-01-28 CN claimed
CN-116519923-A Detection method of inducer in induced rat hyperuricemia kidney injury model 四川大学华西医院 2023-08-01 CN claimed
CN-107541103-A A kind of indoor anti-radiation building coating and preparation method thereof 佛山市三水区嫚娅环保科技有限公司 2018-01-05 CN claimed
CN-105906629-A Technological process for synthesizing adenine 宿迁远扬生物科技有限公司 2016-08-31 CN claimed
EP-2157182-A2 Modified short interfering RNA Qiagen GmbH (DE) 2010-02-24 EP claimed
CN-119264184-B Preparation method of dideoxy ring-opened ribonucleotide triphosphate and intermediate 天津奥利芙生物技术有限公司 2025-03-28 CN disclosed
CN-119375400-A Sample pretreatment method for detecting CD38 enzyme activity in whole blood sample and method for detecting blood CD38 enzyme activity by high performance liquid chromatography 北京医院 2025-01-28 CN disclosed
CN-119264184-A Preparation method of dideoxy ring-opened ribonucleotide triphosphate and intermediate 天津奥利芙生物技术有限公司 2025-01-07 CN disclosed
CN-117069723-A Refining method of pharmaceutical grade adenine 江西阿尔法高科药业有限公司 2023-11-17 CN disclosed
CN-116519923-A Detection method of inducer in induced rat hyperuricemia kidney injury model 四川大学华西医院 2023-08-01 CN disclosed
CN-116334028-A Nucleoside hydrolase mutant, engineering bacterium and application 浙江工业大学 2023-06-27 CN disclosed
CN-112143662-B Recombinant pichia pastoris engineering bacteria and application thereof in preparation of purine 浙江工业大学 2023-01-06 CN disclosed
US-8859749-B2 Modified short interfering RNA QIAGEN GMBH (DE) 2014-10-14 US disclosed
EP-2157182-A2 Modified short interfering RNA Qiagen GmbH (DE) 2010-02-24 EP disclosed
US-20090197332-A1 Modified Short Interfering RNA QIAGEN GMBH (DE) 2009-08-06 US disclosed
EP-1863912-A2 MODIFIED SHORT INTERFERING RNA Qiagen GmbH (DE) 2007-12-12 EP disclosed
WO-2006102970-A2 MODIFIED SHORT INTERFERING RNA QIAGEN GMBH (DE) 2006-10-05 WO disclosed
US-20060167241-A1 Method for synthesizing cyclic bisdinucleoside MITSUI CHEMICALS, INC. (JP) 2006-07-27 US disclosed
EP-1645561-A1 METHOD OF SYNTHESIZING CYCLIC BISDINUCLEOSIDE Mitsui Chemicals, Inc. (JP) 2006-04-12 EP disclosed
WO-1992011276-A1 NOVEL SYNTHESIS OF 2'-'UP' FLUORINATED 2''-DEOXY-ARABINOFURANOSYLPURINES SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) 1992-07-09 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090197332-A1 Modified Short Interfering RNA NSUN2, NSUN3, METTL16 GDA 1238/4885PDPK1 4708/4885MGMT 1172/4885
US-20060167241-A1 Method for synthesizing cyclic bisdinucleoside NSUN2, POLR2H, POLB GDA 716/4885PDPK1 3656/4885MGMT 408/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.