SCHEMBL2808366

SCHEMBL2808366

CCCCCc1cc(C(=O)O)ccc1C

nearest known ligand 0.56

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RARB P10826 9/20 0.56
MEN1 O00255 1/20 0.51
ALDH1A1 P00352 1/20 0.51
RARA P10276 1/20 0.51
MAPT P10636 1/20 0.51
MTOR P42345 1/20 0.51
KMT2A Q03164 1/20 0.51
TP53 P04637 1/20 0.49
TSHR P16473 1/20 0.49
PLA2G4B P0C869 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27889925 0.98 RARB (0.58) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL2811083 0.98 RARB (0.58) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL27889921 0.98 RARB (0.58) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL27906429 0.98 RARB (0.58) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL2807448 0.95 RARB (0.51) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL2809375 0.88 MRGPRX4 (0.48) RARBALDH1A1MAPTTSHR
SCHEMBL27637429 0.86 MRGPRX4 (0.51) MEN1ALDH1A1MAPTKMT2ATP53
SCHEMBL16897565 0.85 MRGPRX4 (0.46) RARBMEN1ALDH1A1RARAKMT2A
SCHEMBL7934928 0.85 RARB (0.54) RARBMEN1ALDH1A1RARAMAPT
SCHEMBL14118067 0.85 RARB (0.57) RARBMEN1ALDH1A1RARAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100068439-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA North aAmerica S.ar.I (US) 2010-03-18 US claimed
WO-2008095071-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA TECHNOLOGIES S.AR.L. (CH) 2008-08-07 WO claimed
EP-3260920-A1 TONER COMPOSITIONS WITH ANTIPLASTICIZERS Xerox Corporation (US) 2017-12-27 EP disclosed
US-9684257-B1 Toner compositions with antiplasticizers XEROX CORPORATION (US) 2017-06-20 US disclosed
US-20100068439-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA North aAmerica S.ar.I (US) 2010-03-18 US disclosed
WO-2008095071-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA TECHNOLOGIES S.AR.L. (CH) 2008-08-07 WO disclosed