SCHEMBL2807448

SCHEMBL2807448

CCCCc1cc(C(=O)O)ccc1C

nearest known ligand 0.51

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
RARB P10826 7/20 0.51
RXRA P19793 1/20 0.47
TP53 P04637 1/20 0.46
TSHR P16473 1/20 0.46
MRGPRX4 Q96LA9 1/20 0.46
PLA2G4B P0C869 1/20 0.45
MEN1 O00255 1/20 0.45
ALDH1A1 P00352 1/20 0.45
RARA P10276 1/20 0.45
MAPT P10636 1/20 0.45
MTOR P42345 1/20 0.45
KMT2A Q03164 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2808366 0.95 RARB (0.56) RARBTP53TSHRPLA2G4BMEN1
SCHEMBL27889921 0.93 RARB (0.58) RARBTP53TSHRPLA2G4BMEN1
SCHEMBL27889925 0.93 RARB (0.58) RARBTP53TSHRPLA2G4BMEN1
SCHEMBL2811083 0.93 RARB (0.58) RARBTP53TSHRPLA2G4BMEN1
SCHEMBL27906429 0.93 RARB (0.58) RARBTP53TSHRPLA2G4BMEN1
SCHEMBL2809375 0.89 MRGPRX4 (0.48) RARBRXRATSHRMRGPRX4ALDH1A1
SCHEMBL21443919 0.87 RARB (0.62) RARBRXRAMEN1ALDH1A1RARA
SCHEMBL27637429 0.87 MRGPRX4 (0.51) RXRATP53TSHRMRGPRX4MEN1
SCHEMBL28407110 0.86 RARB (0.54) RARBRXRATP53TSHRPLA2G4B
SCHEMBL29827702 0.86 PKM (0.46) RARBTSHRMEN1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100068439-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA North aAmerica S.ar.I (US) 2010-03-18 US claimed
WO-2008095071-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA TECHNOLOGIES S.AR.L. (CH) 2008-08-07 WO claimed
US-4276193-A MAGNESIUM DIHALIDE CARRIER, CATALYST COMPRISING AN ELECTRON DONOR, TITANIUM TETRACHLORIDE REDUCED WITH AN ORGANOALUMINUM HALIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-06-30 US claimed
EP-3604281-A1 2(1H)-QUINOLINONE DERIVATIVE Taisho Pharmaceutical Co., Ltd. (JP) 2020-02-05 EP disclosed
EP-3260920-A1 TONER COMPOSITIONS WITH ANTIPLASTICIZERS Xerox Corporation (US) 2017-12-27 EP disclosed
US-9684257-B1 Toner compositions with antiplasticizers XEROX CORPORATION (US) 2017-06-20 US disclosed
US-8895773-B2 Manufacture and use of alkyl p-toluates INVISTA NORTH AMERICA S.A.R.L. (US) 2014-11-25 US disclosed
US-20100068439-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA North aAmerica S.ar.I (US) 2010-03-18 US disclosed
US-20090286912-A1 MANUFACTURE AND USE OF ALKYL p-TOLUATES INVISTA NORTH AMERICA S.A R.L. (US) 2009-11-19 US disclosed
WO-2008095071-A1 POLYESTER COMPOSITION WITH IMPROVED GAS BARRIER PROPERTIES AND ARTICLES THEREOF INVISTA TECHNOLOGIES S.AR.L. (CH) 2008-08-07 WO disclosed
EP-0008764-B1 PROCESS FOR THE PREPARATION OF A CATALYST ON A SOLID CARRIER AND ITS USE IN THE POLYMERISATION OF PROPYLENE BAYER AG (DE) 1982-09-22 EP disclosed
US-4276193-A MAGNESIUM DIHALIDE CARRIER, CATALYST COMPRISING AN ELECTRON DONOR, TITANIUM TETRACHLORIDE REDUCED WITH AN ORGANOALUMINUM HALIDE BAYER AKTIENGESELLSCHAFT (DE) 1981-06-30 US disclosed
EP-0008764-A2 Process for the preparation of a catalyst on a solid carrier and its use in the polymerisation of propylene BAYER AG (DE) 1980-03-19 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090286912-A1 MANUFACTURE AND USE OF ALKYL p-TOLUATES EP300, TERT, NAPEPLD RARB 2131/4885RXRA 2262/4885TP53 1455/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.