Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 4/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.35 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 5/20 | 0.34 |
| ▸ | PPARD | Q03181 | 5/20 | 0.34 |
| ▸ | PPARA | Q07869 | 5/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL27503459 | 0.90 | TSHR (0.40) | TSHRALDH1A1ABCC4MAPTTP53 | |
| Sebacic Acid SCHEMBL27555093 | 0.89 | ALDH1A1 (0.42) | TSHRALDH1A1ABCC4MAPTLMNA | |
| Adipic Acid SCHEMBL27503108 | 0.88 | ALDH1A1 (0.46) | TSHRALDH1A1ABCC4MAPTTP53 | |
| Adipic Acid SCHEMBL27649162 | 0.88 | TSHR (0.50) | TSHRALDH1A1ABCC4MAPTLMNA | |
| Acrylic Acid Methyl Ester SCHEMBL27544299 | 0.88 | ALDH1A1 (0.45) | TSHRALDH1A1TP53CYP3A4MAPK1 | |
| Sebacic Acid SCHEMBL27488122 | 0.87 | ALDH1A1 (0.44) | TSHRALDH1A1ABCC4MAPTTP53 | |
| Pimelic Acid SCHEMBL28082958 | 0.87 | ALDH1A1 (0.44) | TSHRALDH1A1ABCC4MAPTTP53 | |
| Pimelic Acid SCHEMBL28832352 | 0.85 | ALDH1A1 (0.43) | TSHRALDH1A1ABCC4MAPTTP53 | |
| Sebacic Acid SCHEMBL28083155 | 0.85 | ALDH1A1 (0.43) | TSHRALDH1A1ABCC4MAPTTP53 | |
| Pivalate SCHEMBL27599809 | 0.84 | ALDH1A1 (0.40) | TSHRALDH1A1TP53CYP3A4MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105829999-A | Optical sheet, conductive sheet, and display device provided with same | 王子控股株式会社 | 2016-08-03 | — | — | CN | disclosed |