Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894351 | 0.88 | SMN1; SMN2 (0.46) | CYP2C9SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL28084226 | 0.85 | CDK4 (0.46) | SMN1; SMN2NPC1RAB9ATSHRCYP1A2 | |
| SCHEMBL8592978 | 0.83 | SMN1; SMN2 (0.54) | CYP2C9SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL18241048 | 0.83 | CYP2C9 (0.54) | CYP2C9SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL13794084 | 0.82 | KDM4E (0.51) | CYP2C9SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL27434536 | 0.81 | CYP2C9 (0.52) | CYP2C9SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL27437488 | 0.80 | SMN1; SMN2 (0.46) | CYP2C9SMN1; SMN2TSHRPPARATTR | |
| SCHEMBL28038435 | 0.80 | CYP2C9 (0.45) | CYP2C9SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL27814043 | 0.80 | SMN1; SMN2 (0.51) | CYP2C9SMN1; SMN2NPC1RAB9ATSHR | |
| SCHEMBL8195105 | 0.79 | CYP2C9 (0.50) | CYP2C9SMN1; SMN2NPC1RAB9ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588657-B | The manufacture method of phenylacetyl amines | 住友化学株式会社 | 2016-06-22 | — | — | CN | disclosed |