Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK4 | P11802 | 1/20 | 0.46 |
| ▸ | CCND1 | P24385 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | RXRB | P28702 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12894353 | 0.87 | CDK4 (0.44) | CDK4CCND1FFAR1FFAR4RXRA | |
| SCHEMBL28084205 | 0.85 | CYP2C9 (0.47) | FFAR1FFAR4MEN1KMT2ANPC1 | |
| SCHEMBL13154275 | 0.82 | FFAR1 (0.57) | CDK4CCND1FFAR1FFAR4RXRA | |
| SCHEMBL17328307 | 0.81 | RXRA (0.49) | CDK4CCND1FFAR1FFAR4RXRA | |
| SCHEMBL22138645 | 0.80 | CDK4 (0.53) | CDK4CCND1RXRARXRBRXRG | |
| SCHEMBL3521430 | 0.79 | CDK4 (0.60) | CDK4CCND1RXRARXRBRXRG | |
| SCHEMBL28038052 | 0.78 | FFAR1 (0.43) | CDK4CCND1FFAR1FFAR4RXRA | |
| SCHEMBL13794253 | 0.78 | CDK4 (0.51) | CDK4CCND1RXRARXRBRXRG | |
| Bromide SCHEMBL27650271 | 0.77 | CDK4 (0.58) | CDK4CCND1RXRARXRBRXRG | |
| SCHEMBL12894342 | 0.76 | MAPT (0.45) | CDK4CCND1FFAR1FFAR4RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103588657-B | The manufacture method of phenylacetyl amines | 住友化学株式会社 | 2016-06-22 | — | — | CN | disclosed |