SCHEMBL28084243

SCHEMBL28084243

CCCCCCC1=C(C=O)CCCC1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCD O00767 1/20 0.41
HIF1A Q16665 2/20 0.38
EPAS1 Q99814 1/20 0.38
THRA P10827 4/20 0.35
THRB P10828 4/20 0.35
TSHR P16473 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CCR5 P51681 2/20 0.33
S1PR2 O95136 1/20 0.33
S1PR4 O95977 1/20 0.33
S1PR1 P21453 1/20 0.33
S1PR3 Q99500 1/20 0.33
ESR1 P03372 2/20 0.32
ADRA2A P08913 2/20 0.32
ADORA3 P0DMS8 2/20 0.32
TACR2 P21452 2/20 0.32
SLC6A2 P23975 2/20 0.32
SLC6A4 P31645 2/20 0.32
SLC6A3 Q01959 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28102844 1.00 SCD (0.41) SCDHIF1AEPAS1THRATHRB
SCHEMBL9446255 0.98 SCD (0.38) SCDHIF1AEPAS1THRATHRB
SCHEMBL16976827 0.76
SCHEMBL678379 0.75 MEN1 (0.42) SCDHIF1ATHRBTSHRMEN1
SCHEMBL5346762 0.75 SCD (0.47) SCDHIF1ATHRBTSHRMEN1
SCHEMBL20339953 0.75 MEN1 (0.42) SCDHIF1ATHRBTSHRMEN1
Bicarbonate SCHEMBL9478968 0.75 SCD (0.58) SCDTSHRMEN1KMT2AESR1
SCHEMBL17634359 0.74
SCHEMBL29482102 0.73 SCD (0.33) SCDHIF1AEPAS1
SCHEMBL29482108 0.73 SCD (0.33) SCDHIF1AEPAS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105693590-B A kind of photothermal reagent and its preparation method and application of pH control tumor cell 复旦大学 2019-01-15 CN disclosed
CN-105693590-A Photothermal reagent for identifying tumor cells through pH control and preparation method and application thereof 复旦大学 2016-06-22 CN disclosed