SCHEMBL28084299

SCHEMBL28084299

CCc1ccc(C#Cc2ccc(OB(O)O)cc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 1/20 0.42
LPL P06858 1/20 0.42
LIPG Q9Y5X9 1/20 0.42
ACACB O00763 12/20 0.42
RXRA P19793 1/20 0.39
RXRB P28702 1/20 0.39
APP P05067 1/20 0.39
CYP2C19 P33261 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2126535 0.89 LPL (0.52) CYP2A6LPLLIPGRXRARXRB
SCHEMBL7851797 0.83 LPL (0.47) LPLLIPGRXRARXRBCYP2C19
SCHEMBL8228398 0.78 CYP2A6 (0.64) CYP2A6LPLLIPGACACBAPP
SCHEMBL5050178 0.78 CYP2A6 (0.64) CYP2A6LPLLIPGACACBAPP
SCHEMBL13433660 0.77 NQO1 (0.58) ACACB
SCHEMBL4799978 0.77 APP (0.59) CYP2A6ACACBAPPSMN1; SMN2
SCHEMBL9509352 0.76 ACACB (0.56) CYP2A6ACACB
SCHEMBL28464653 0.73 LPL (0.48) LPLLIPGRXRARXRBCYP2C19
SCHEMBL761972 0.73 LPL (0.55) LPLLIPG
SCHEMBL9509270 0.73 CYP2A6 (0.44) CYP2A6ACACBRXRARXRBAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104263380-B A kind of liquid-crystal compounds with high birefringence rate and wide nematic phase temperature range and combinations thereof thing 西安近代化学研究所 2016-08-17 CN disclosed