Fluoride

Fluoride

SCHEMBL28084339

ClC(Cl)(Cl)c1ccccc1.F

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.93
CYP1A2 P05177 1/20 0.48
KCNN4 O15554 5/20 0.45
ALDH1A1 P00352 3/20 0.45
MAPK1 P28482 1/20 0.39
LMNA P02545 1/20 0.39
TAAR1 Q96RJ0 1/20 0.36
ALOX15 P16050 1/20 0.36
PTPN1 P18031 1/20 0.35
ESR1 P03372 1/20 0.35
CYP3A4 P08684 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL522316 0.97 TSHR (1.00) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL27351108 0.93 TSHR (0.93) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL28581636 0.93 TSHR (0.93) TSHRCYP1A2KCNN4ALDH1A1MAPK1
SCHEMBL30740351 0.93 TSHR (0.93) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL28846684 0.90 TSHR (0.88) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Ethane SCHEMBL28666542 0.90 TSHR (0.88) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Biphenyl SCHEMBL28542053 0.88 TSHR (0.82) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Methyl Alcohol SCHEMBL28788630 0.88 TSHR (0.82) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Methylene Chloride SCHEMBL28935108 0.88 TSHR (0.82) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL19409802 0.85 TSHR (0.78) TSHRCYP1A2KCNN4ALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105693480-A Method for catalyzing arenes or heteroarenes to be subjected to trifluoromethylation by semiconductor photocatalysts 福州大学 2016-06-22 CN disclosed