SCHEMBL28084385

SCHEMBL28084385

O=C1c2cc(Br)ccc2C(=O)c2c(Cl)cccc21

nearest known ligand 0.58

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PTPRC P08575 1/20 0.58
BCL2 P10415 2/20 0.51
MCL1 Q07820 1/20 0.51
S100A4 P26447 2/20 0.50
NSD2 O96028 1/20 0.48
CYP1A2 P05177 2/20 0.46
MAPK1 P28482 2/20 0.46
TTR P02766 2/20 0.43
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
ADORA2A P29274 2/20 0.41
CHRM5 P08912 1/20 0.40
EDNRB P24530 1/20 0.39
EDNRA P25101 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6899117 0.83 S100A4 (0.61) PTPRCBCL2MCL1S100A4NSD2
SCHEMBL31375388 0.83 S100A4 (0.61) PTPRCBCL2MCL1S100A4NSD2
SCHEMBL6907201 0.83 PTPRC (0.61) PTPRCBCL2MCL1S100A4CYP1A2
SCHEMBL6905719 0.83 PTPRC (0.61) PTPRCBCL2MCL1S100A4CYP1A2
SCHEMBL6906411 0.83 S100A4 (0.61) PTPRCBCL2MCL1S100A4NSD2
Anthraquinone SCHEMBL5172785 0.82 ADORA2A (0.57) PTPRCBCL2MCL1NSD2MAPK1
SCHEMBL36815 0.82 ADORA2A (0.57) PTPRCBCL2MCL1NSD2MAPK1
SCHEMBL29401197 0.82 ADORA2A (0.57) PTPRCBCL2MCL1NSD2MAPK1
Anthraquinone SCHEMBL28163374 0.81 S100A4 (0.65) PTPRCBCL2MCL1S100A4NSD2
SCHEMBL30610015 0.80 ELANE (0.65) NSD2CYP1A2MAPK1TTRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105694529-B Cationic reactive dye containing polyether amine chain segment and preparation method thereof 南京工业大学 2017-06-23 CN disclosed
CN-105694529-A Cationic reactive dye containing polyether amine chain segment and preparation method thereof 南京工业大学 2016-06-22 CN disclosed