Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL28826899 | 0.83 | TSHR (0.62) | TSHRHPGDCA2CA1CYP3A4 | |
| Acrylic Acid Methyl Ester SCHEMBL27704592 | 0.83 | TSHR (0.62) | TSHRHPGDCA2CA1CYP3A4 | |
| Acrylic Acid Methyl Ester SCHEMBL27692903 | 0.82 | TSHR (0.69) | TSHRHPGDCA2CA1CYP3A4 | |
| Acrylic Acid Methyl Ester SCHEMBL3214910 | 0.81 | TSHR (0.88) | TSHRHPGDCA2CA1CYP3A4 | |
| Acrylic Acid Methyl Ester SCHEMBL15418484 | 0.79 | TSHR (0.57) | TSHRHPGDCA2CA1CYP3A4 | |
| SCHEMBL8017021 | 0.79 | ALDH1A1 (0.50) | TSHRCA2CA1CYP3A4TDP1 | |
| Acrylic Acid Methyl Ester SCHEMBL9719491 | 0.77 | TSHR (0.81) | TSHRHPGDCA2CA1CYP3A4 | |
| Acrylic Acid Ethyl Ester SCHEMBL18424749 | 0.77 | TSHR (0.81) | TSHRHPGDCA2CA1CYP3A4 | |
| SCHEMBL28056322 | 0.77 | ALDH1A1 (0.48) | TSHRCA2CA1CYP3A4TDP1 | |
| Acrylic Acid Methyl Ester SCHEMBL27538149 | 0.77 | TSHR (0.50) | TSHRHPGDCA2CA1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109073783-A | Manufacture the method with the silicone hydrogel contact lenses of reduced evaporation rate | 库柏维景国际控股公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108700676-A | The silicone hydrogel contact lenses of improved lubricity | 库柏维景国际控股公司 | 2018-10-23 | — | — | CN | disclosed |
| CN-106573423-B | Method of making wettable silicone hydrogel contact lenses | 库柏维景国际控股公司 | 2018-07-03 | — | — | CN | disclosed |
| CN-106573423-A | Method of making wettable silicone hydrogel contact lenses | 库柏维景国际控股公司 | 2017-04-19 | — | — | CN | disclosed |
| CN-103827175-B | Silicone hydrogel contact lenses | 库柏维景国际控股公司 | 2016-08-10 | — | — | CN | disclosed |