Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 2/20 | 0.34 |
| ▸ | FABP4 | P15090 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | TYMS | P04818 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.32 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28084657 | 0.93 | KMT2A (0.40) | KMT2AABCB11FABP3FABP4ALDH1A1 | |
| SCHEMBL28084654 | 0.77 | KDM4E (0.33) | KMT2AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL28767893 | 0.77 | PLAU (0.39) | KMT2AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27785390 | 0.77 | ERN1 (0.47) | KMT2AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27304277 | 0.75 | ALDH1A1 (0.53) | KMT2AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27661280 | 0.73 | ALDH1A1 (0.61) | KMT2AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL28175642 | 0.73 | ERN1 (0.45) | KMT2AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL28084655 | 0.73 | ERN1 (0.36) | KMT2AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL27810256 | 0.72 | ALDH1A1 (0.59) | KMT2AALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL5427708 | 0.72 | ALDH1A1 (0.44) | KMT2AALDH1A1HPGDHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105837478-B | As P2X3And P2X2/3The double 9 oxime derivates of double sulfonyl amerantrones of receptor antagonist | 成都理工大学 | 2017-11-14 | — | — | CN | disclosed |
| CN-105837478-A | Bisulfonyl anthracenedione dioxime derivative serving as P2X<3> and P2X<2/3> receptor antagonists | 成都理工大学 | 2016-08-10 | — | — | CN | disclosed |