SCHEMBL28085114

SCHEMBL28085114

O=C(O)c1ccc(C=C(O)C(CO)(CO)CO)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.52
TDP1 Q9NUW8 2/20 0.52
GLA P06280 1/20 0.52
POLB P06746 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TSHR P16473 2/20 0.46
TP53 P04637 1/20 0.46
KMT2A Q03164 1/20 0.46
RARA P10276 2/20 0.42
RARB P10826 2/20 0.42
RARG P13631 2/20 0.42
LMNA P02545 1/20 0.42
HTT P42858 1/20 0.42
SRD5A2 P31213 1/20 0.41
FBP1 P09467 1/20 0.41
CA1 P00915 2/20 0.40
CA2 P00918 2/20 0.40
CA12 O43570 1/20 0.40
CA3 P07451 1/20 0.40
TYR P14679 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2222005 0.87 ALDH1A1 (0.50) ALDH1A1TDP1GLAPOLBL3MBTL1
SCHEMBL28085120 0.83 ALDH1A1 (0.41) ALDH1A1TDP1GLAPOLBL3MBTL1
SCHEMBL1304100 0.76 CYP2A6 (0.38) ALDH1A1POLBKMT2ACA1HPGD
SCHEMBL8580744 0.74 ALDH1A1 (0.68) ALDH1A1TDP1GLAPOLBL3MBTL1
Terephthalic Acid SCHEMBL2687529 0.72 TSHR (0.63) ALDH1A1TSHRTP53SRD5A2CA1
Terephthalic Acid SCHEMBL11490240 0.72 TSHR (0.63) ALDH1A1TSHRTP53SRD5A2CA1
Terephthalic Acid SCHEMBL8506032 0.72 TSHR (0.63) ALDH1A1TSHRTP53SRD5A2CA1
SCHEMBL17685853 0.72 ALDH1A1 (0.52) ALDH1A1TSHRTP53LMNAHPGD
Ethylene Glycol SCHEMBL10660552 0.71 ALDH1A1 (0.58) ALDH1A1TDP1GLAPOLBL3MBTL1
Terephthalic Acid SCHEMBL10952725 0.71 ALDH1A1 (0.58) ALDH1A1TDP1GLAPOLBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102712787-B Based on acetal compound for polyolefinic nucleator 瑞来斯实业公司 2016-08-17 CN claimed
CN-102712787-B Based on acetal compound for polyolefinic nucleator 瑞来斯实业公司 2016-08-17 CN disclosed