Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15418336 | 0.73 | KMT2A (0.35) | TP53KMT2A | |
| SCHEMBL1964113 | 0.72 | — | — | |
| SCHEMBL27831921 | 0.70 | — | — | |
| SCHEMBL20495492 | 0.70 | — | — | |
| SCHEMBL3337826 | 0.70 | — | — | |
| SCHEMBL29008890 | 0.69 | — | — | |
| SCHEMBL11830624 | 0.69 | KMT2A (0.47) | PKMTDP1KMT2A | |
| SCHEMBL9275882 | 0.68 | — | — | |
| SCHEMBL26913115 | 0.68 | — | — | |
| SCHEMBL30684960 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109528758-A | A kind of composition improving sleep | 孙军 | 2019-03-29 | — | — | CN | disclosed |
| CN-109232423-A | The method that one kettle way replaces alkynes and hydrazine or hydrazine substituent reaction to prepare multi-substituted pyrazol | 江苏大学 | 2019-01-18 | — | — | CN | disclosed |
| CN-106806351-A | A kind of preparation with zolpidem as main chemical compositions and preparation method thereof | 成都绿林科技有限公司 | 2017-06-09 | — | — | CN | disclosed |
| CN-104262256-B | Utilize the method that α, beta-unsaturated carbonyl compound prepare multi-substituted pyrazol compounds | 江苏大学 | 2016-08-17 | — | — | CN | disclosed |