Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.32 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.32 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.32 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.32 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.32 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.32 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3337826 | 0.88 | — | — | |
| SCHEMBL28085155 | 0.73 | TP53 (0.34) | KMT2ATP53 | |
| SCHEMBL27949468 | 0.73 | CA12 (0.34) | KMT2AALDH1A1PPARGLMNATP53 | |
| SCHEMBL6970368 | 0.72 | — | — | |
| SCHEMBL19121290 | 0.72 | HPGD (0.30) | — | |
| SCHEMBL6654827 | 0.69 | KDM4E (0.38) | KMT2AALDH1A1LMNAMAPK1 | |
| SCHEMBL17647210 | 0.69 | GABRP (0.41) | — | |
| SCHEMBL23674569 | 0.69 | — | — | |
| SCHEMBL5838870 | 0.69 | GRIN2D (0.33) | LMNA | |
| SCHEMBL4275360 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103547571-A | Method for producing pyrazolecarboxylic acid derivative | SHIONOGI & CO | 2014-01-29 | — | — | CN | disclosed |
| EP-2687515-A1 | METHOD FOR PRODUCING PYRAZOLECARBOXYLIC ACID DERIVATIVE | Shionogi & Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |
| US-20140012013-A1 | METHOD FOR PRODUCING PYRAZOLE CARBOXYLIC ACID DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140012013-A1 | METHOD FOR PRODUCING PYRAZOLE CARBOXYLIC ACID DERIVATIVE | HSD11B1, HSD11B2, HSD17B1 | KMT2A 3174/4885PARP10 2598/4885ALDH1A1 115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.