SCHEMBL28085288

SCHEMBL28085288

Cc1ccc(N)c(F)c1.Nc1ccccc1F

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.48
SMN1; SMN2 Q16637 2/20 0.48
ALOX15 P16050 2/20 0.48
CYP3A4 P08684 2/20 0.48
TP53 P04637 1/20 0.48
THRB P10828 1/20 0.48
ALDH1A1 P00352 4/20 0.46
NFE2L2 Q16236 2/20 0.44
KIF11 P52732 1/20 0.41
ACHE P22303 1/20 0.39
HDAC1 Q13547 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
HSD17B10 Q99714 1/20 0.39
NPC1 O15118 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
CA1 P00915 2/20 0.38
CA12 O43570 1/20 0.38
CA2 P00918 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17613 0.89
SCHEMBL29417984 0.89
Phenol SCHEMBL27884915 0.82 ALDH1A1 (0.48) TDP1SMN1; SMN2ALOX15CYP3A4TP53
Ethane SCHEMBL1703921 0.79 CYP3A4 (0.50) TDP1SMN1; SMN2ALOX15CYP3A4ALDH1A1
SCHEMBL29410382 0.79
SCHEMBL33295 0.79
Methyl Alcohol SCHEMBL27906609 0.77 CYP3A4 (0.47) TDP1SMN1; SMN2ALOX15CYP3A4ALDH1A1
Bromide SCHEMBL25169235 0.77
Methane SCHEMBL1702520 0.77
Hydrochloric Acid SCHEMBL3152989 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104628503-B A kind of method of ethylene oligomerization 中国石油化工股份有限公司 2016-08-17 CN disclosed