SCHEMBL28085346

SCHEMBL28085346

C=NC(=O)NC(=O)NC(N)=O

nearest known ligand 0.36

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.36
CYP1A2 P05177 2/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 2/20 0.30
NFKB1 P19838 2/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30
THPO P40225 1/20 0.30
CA2 P00918 1/20 0.30
LMNA P02545 1/20 0.30
CYP3A4 P08684 1/20 0.30
CA5A P35218 1/20 0.30
BLM P54132 1/20 0.30
PMP22 Q01453 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27805257 0.87
SCHEMBL460415 0.87
SCHEMBL653996 0.78 CRBN (0.53) CRBNCYP1A2POLBTSHRNFKB1
SCHEMBL29509273 0.74 CRBN (0.50) CRBNCYP1A2POLBTSHRNFKB1
SCHEMBL27715006 0.74 TSHR (0.53) CRBNCYP1A2POLBTSHRNFKB1
SCHEMBL29509217 0.74 CRBN (0.50) CRBNCYP1A2POLBTSHRNFKB1
SCHEMBL27905681 0.74 CRBN (0.50) CRBNCYP1A2POLBTSHRNFKB1
SCHEMBL18781183 0.72
Carbamic Acid SCHEMBL27715066 0.72 ACHE (0.50) CRBNCYP1A2POLBTSHRNFKB1
SCHEMBL10406051 0.70 CRBN (0.41) CRBNCYP1A2POLBTSHRNFKB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107266338-B The manufacturing method of isocyanates 旭化成株式会社 2019-10-11 CN disclosed
CN-105026367-B Method for producing isothiocyanate 旭化成株式会社 2019-05-21 CN disclosed
CN-109633008-A A kind of method of a methylenediourea and dimethylene triurea in detection urea-formaldehyde fertilizer 沈阳中科新型肥料有限公司 2019-04-16 CN disclosed
CN-108976155-A The manufacturing method of isothiocyanates 旭化成株式会社 2018-12-11 CN disclosed
CN-103553972-B Method for the preparation of n-substituted carbamic acid ester and method for the preparation of isocyanate using the n-substituted carbamic acid ester 旭化成株式会社 2017-04-12 CN disclosed
CN-103588680-B N-substituted carbamate conveying with and storage compositions and manufacture isocyanates method 旭化成株式会社 2016-08-10 CN disclosed