SCHEMBL28085441

SCHEMBL28085441

C=Cc1cccc(C=C)c1C=C.C=Cc1ccccc1C

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.46
TSHR P16473 4/20 0.46
ACHE P22303 2/20 0.38
KDM4E B2RXH2 3/20 0.35
RAB9A P51151 3/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2C19 P33261 1/20 0.35
APOBEC3A P31941 1/20 0.35
APOBEC3G Q9HC16 1/20 0.35
TP53 P04637 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
PABPC1 P11940 1/20 0.34
CYP2A6 P11509 2/20 0.33
TTR P02766 1/20 0.33
CYP2D6 P10635 1/20 0.33
THPO P40225 1/20 0.33
HIF1A Q16665 1/20 0.33
NR1H2 P55055 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6469766 0.89 ALDH1A1 (0.38) ALDH1A1TSHRACHEKDM4ECYP1A2
SCHEMBL678151 0.89 ALDH1A1 (0.56) ALDH1A1TSHRACHEKDM4ERAB9A
SCHEMBL14887 0.89
SCHEMBL29391686 0.89
SCHEMBL7921184 0.87 ALDH1A1 (0.41) ALDH1A1TSHRACHEKDM4ERAB9A
SCHEMBL41438 0.86 ALDH1A1 (0.39) ALDH1A1TSHRACHEKDM4ECYP1A2
SCHEMBL30332485 0.86 ALDH1A1 (0.39) ALDH1A1TSHRACHEKDM4ECYP1A2
SCHEMBL16109755 0.86 ALDH1A1 (0.54) ALDH1A1TSHRACHEKDM4ERAB9A
Benzene SCHEMBL11895034 0.86 TSHR (0.54) ALDH1A1TSHRACHEKDM4ERAB9A
SCHEMBL7547692 0.86 ALDH1A1 (0.54) ALDH1A1TSHRACHEKDM4ERAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105899288-A Method to provide pipeline quality natural gas 陶氏环球技术有限责任公司 2016-08-24 CN disclosed