Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | CIT | O14578 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ADCY6 | O43306 | 1/20 | 0.49 |
| ▸ | ADCY3 | O60266 | 1/20 | 0.49 |
| ▸ | ADCY9 | O60503 | 1/20 | 0.49 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.49 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.49 |
| ▸ | GCGR | P47871 | 1/20 | 0.49 |
| ▸ | ADCY7 | P51828 | 1/20 | 0.49 |
| ▸ | ADCY2 | Q08462 | 1/20 | 0.49 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.49 |
| ▸ | ADCY4 | Q8NFM4 | 1/20 | 0.49 |
| ▸ | NAMPT | P43490 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085618 | 1.00 | BACE1 (0.56) | BACE1MAPTALDH1A1HDAC8CIT | |
| SCHEMBL21880198 | 0.86 | MAPT (0.65) | BACE1MAPTALDH1A1HDAC8CIT | |
| SCHEMBL21880197 | 0.86 | MAPT (0.65) | BACE1MAPTALDH1A1HDAC8CIT | |
| SCHEMBL2312372 | 0.85 | BACE1 (0.63) | BACE1HDAC8CITMEN1NPC1 | |
| SCHEMBL28279157 | 0.85 | BACE1 (0.63) | BACE1HDAC8CITMEN1NPC1 | |
| SCHEMBL2312361 | 0.85 | BACE1 (0.63) | BACE1HDAC8CITMEN1NPC1 | |
| SCHEMBL23092855 | 0.84 | NAMPT (0.54) | BACE1HDAC8CITMEN1NPC1 | |
| SCHEMBL23092854 | 0.84 | NAMPT (0.54) | BACE1HDAC8CITMEN1NPC1 | |
| SCHEMBL29002157 | 0.84 | MAPK1 (0.63) | BACE1ALDH1A1HDAC8CITMEN1 | |
| SCHEMBL28085751 | 0.84 | MAPK1 (0.63) | BACE1ALDH1A1HDAC8CITMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105732413-B | The synthesis technique of chiral N aryl amino acids acid amides | 成都理工大学 | 2017-08-25 | — | — | CN | disclosed |
| CN-105732413-A | Synthetic process of chiral N-aromatic amino acid amide | 成都理工大学 | 2016-07-06 | — | — | CN | disclosed |