Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.63 |
| ▸ | ALPI | P09923 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.61 |
| ▸ | XIAP | P98170 | 1/20 | 0.61 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.61 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.57 |
| ▸ | CTSC | P53634 | 1/20 | 0.56 |
| ▸ | AKT1 | P31749 | 1/20 | 0.55 |
| ▸ | CIT | O14578 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28279157 | 1.00 | BACE1 (0.63) | BACE1HDAC8ALPIPKMPTGS1 | |
| SCHEMBL2312361 | 1.00 | BACE1 (0.63) | BACE1HDAC8ALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL5960990 | 0.98 | HDAC8 (0.65) | BACE1HDAC8ALPIPKMPTGS1 | |
| Hydrochloric Acid SCHEMBL5960992 | 0.98 | HDAC8 (0.65) | BACE1HDAC8ALPIPKMPTGS1 | |
| SCHEMBL11880637 | 0.90 | BACE1 (0.68) | BACE1HDAC8SLC7A5CIT | |
| SCHEMBL16993871 | 0.90 | BACE1 (0.68) | BACE1HDAC8SLC7A5CIT | |
| SCHEMBL23477267 | 0.89 | BACE1 (0.60) | BACE1HDAC8ALPIPKMPTGS1 | |
| SCHEMBL4522561 | 0.89 | MEN1 (0.69) | BACE1HDAC8ALPIPKMPTGS1 | |
| SCHEMBL7289459 | 0.89 | BACE1 (0.60) | BACE1HDAC8ALPIPKMPTGS1 | |
| SCHEMBL9590958 | 0.89 | AKT1 (0.66) | BACE1HDAC8ALPIPKMPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3342599-B1 | HEAT-SENSITIVE RECORDING MATERIAL | SANKO CO LTD (JP) | 2021-06-16 | — | — | EP | disclosed |
| WO-2021110076-A1 | OXAMIDE DERIVATIVES, PREPARATION METHOD THEREFOR AND USE THEREOF IN MEDICINE | 深圳信立泰药业股份有限公司 | 2021-06-10 | — | — | WO | disclosed |
| CN-109438277-A | Oximido naphthoquinone compound and its preparation method and application | 普济生物科技（台州）有限公司 | 2019-03-08 | — | — | CN | disclosed |
| US-10086634-B2 | Heat-sensitive recording material | SANKO CO., LTD. (JP) | 2018-10-02 | — | — | US | disclosed |
| US-20180194151-A1 | HEAT-SENSITIVE RECORDING MATERIAL | SANKO CO., LTD. (JP) | 2018-07-12 | — | — | US | disclosed |
| EP-3342599-A1 | HEAT-SENSITIVE RECORDING MATERIAL | Sanko Co., Ltd. (JP) | 2018-07-04 | — | — | EP | disclosed |
| CN-105732413-B | The synthesis technique of chiral N aryl amino acids acid amides | 成都理工大学 | 2017-08-25 | — | — | CN | disclosed |
| US-8288549-B2 | Glycine B antagonist | MERZ PHARMA GMBH & CO. KGAA (DE) | 2012-10-16 | — | — | US | disclosed |
| US-20120136176-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2012-05-31 | — | — | US | disclosed |
| US-20110190342-A1 | GLYCINE B ANTAGONIST | HENRICH MARKUS | 2011-08-04 | — | — | US | disclosed |
| CN-1264817-C | Certain cyclic thio substitued acylaminoacid amide derivatives | NOVARTIS AG (CH) | 2006-07-19 | — | — | CN | disclosed |
| CN-1313776-A | Therapeutic agent for allergic diseases | FUJI PHARMACEUTICAL INDUSTRY C (JP) | 2001-09-19 | — | — | CN | disclosed |
| US-6114381-A | TO CONTROL BRAIN DAMAGE ASSOCIATED WITH ANOXIA OR ISCHEMIA WHICH TYPICALLY FOLLOWS STROKE, CARDIAC ARREST OR PERINATAL ASPHYXIA; COMPOUND IS AN ANTAGONIST TO INHIBIT EXCITOTOXIC ACTIONS AT EXCITATORY AMINO ACID RECEPTOR SITES | G. D. SEARLE & CO. (US) | 2000-09-05 | — | — | US | disclosed |
| CN-1251092-A | Certain cyclic thio substitued acylaminoacid amide derivatives | NOVARTIS AG (CH) | 2000-04-19 | — | — | CN | disclosed |
| CN-1049651-C | Metalloproteinase inhibitors | BRITISH BIOTECH PHARM (GB) | 2000-02-23 | — | — | CN | disclosed |
| EP-0966439-A1 | CERTAIN CYCLIC THIO SUBSTITUTED ACYLAMINOACID AMIDE DERIVATIVES | Novartis AG (CH) | 1999-12-29 | — | — | EP | disclosed |
| WO-1998042662-A1 | CERTAIN CYCLIC THIO SUBSTITUTED ACYLAMINOACID AMIDE DERIVATIVES | NOVARTIS AG (CH) | 1998-10-01 | — | — | WO | disclosed |
| CN-1138851-A | Metalloproteinase inhibitors | BRITISH BIOTECH PHARM (GB) | 1996-12-25 | — | — | CN | disclosed |
| EP-0740652-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1996-11-06 | — | — | EP | disclosed |
| WO-1995019956-A1 | METALLOPROTEINASE INHIBITORS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 1995-07-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180194151-A1 | HEAT-SENSITIVE RECORDING MATERIAL | ASIC1, SCN1A, NPR1 | BACE1 1609/4885HDAC8 3705/4885ALPI 3464/4885 |
| US-20120136176-A1 | CATALYST FOR ASYMMETRIC HYDROGENATION AND METHOD FOR MANUFACTURING OPTICALLY ACTIVE CARBONYL COMPOUND USING THE SAME | HMOX1, HIRA, HRH1 | BACE1 15/4885HDAC8 2466/4885ALPI 3442/4885 |
| US-10086634-B2 | Heat-sensitive recording material | ASIC1, SCN1A, NPR1 | BACE1 1411/4885HDAC8 3799/4885ALPI 3593/4885 |
| US-20110190342-A1 | GLYCINE B ANTAGONIST | GRIN2B, GLRB, GRIN2A | BACE1 651/4885HDAC8 4794/4885ALPI 4486/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.