Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.74 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.61 |
| ▸ | MAPK14 | Q16539 | 7/20 | 0.53 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.53 |
| ▸ | PDK1 | Q15118 | 6/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | STAT3 | P40763 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14341084 | 0.86 | PDE10A (0.79) | PDE10AMBNL1PDK1TDP1POLB | |
| SCHEMBL14341086 | 0.86 | PDE10A (0.93) | PDE10AMBNL1PDK1TDP1LMNA | |
| SCHEMBL2125225 | 0.85 | PDE10A (1.00) | PDE10AMBNL1PDK1TDP1LMNA | |
| SCHEMBL6858227 | 0.84 | PDE10A (0.96) | PDE10AMBNL1PDK1TDP1LMNA | |
| SCHEMBL30999690 | 0.84 | PDE10A (0.96) | PDE10AMBNL1PDK1TDP1LMNA | |
| SCHEMBL27610987 | 0.84 | PDE10A (0.96) | PDE10AMBNL1PDK1TDP1LMNA | |
| SCHEMBL28531479 | 0.83 | PDE10A (0.70) | PDE10AMBNL1MAPK14PDK1TDP1 | |
| SCHEMBL8735820 | 0.83 | PDE10A (0.65) | PDE10AMBNL1MAPK14PDK1TDP1 | |
| SCHEMBL28853907 | 0.83 | PDE10A (0.74) | PDE10AMBNL1MAPK14PDK1TDP1 | |
| SCHEMBL12970154 | 0.83 | PDE10A (0.74) | PDE10AMBNL1PDK1TDP1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112521333-A | Synthesis method of chiral 2, 3-disubstituted tetrahydroquinoline derivative | 中国科学院大连化学物理研究所 | 2021-03-19 | — | — | CN | disclosed |
| CN-105801630-A | Organometallic complex, and light-emitting element and light-emitting device using the organometallic complex | 株式会社半导体能源研究所 | 2016-07-27 | — | — | CN | disclosed |