Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.55 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.55 |
| ▸ | APP | P05067 | 1/20 | 0.51 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.47 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | PTGES | O14684 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28085736 | 0.86 | ALOX15 (0.54) | MTNR1AMTNR1BAPPSMPD1FFAR4 | |
| SCHEMBL15548395 | 0.86 | ALOX15 (0.63) | ALOX15PPARGPPARA | |
| SCHEMBL15548455 | 0.84 | ALOX15 (0.61) | ALOX15PPARGPPARA | |
| SCHEMBL15547878 | 0.84 | ALOX15 (0.61) | ALOX15PPARGPPARA | |
| SCHEMBL15546557 | 0.84 | ALOX15 (0.61) | ALOX15PPARGPPARA | |
| SCHEMBL15548211 | 0.84 | ALOX15 (0.61) | ALOX15PPARGPPARA | |
| SCHEMBL15549321 | 0.84 | ALOX15 (0.61) | ALOX15PPARGPPARA | |
| SCHEMBL15547399 | 0.84 | ALOX15 (0.61) | ALOX15PPARGPPARA | |
| SCHEMBL15549411 | 0.81 | ALOX15 (0.65) | ALOX15PPARGPPARA | |
| SCHEMBL3804975 | 0.80 | NPC1 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105849111-B | Pyrans and the different cresol derivatives of baynide fibre and metabolic syndrome or treatment of inflammatory diseases pharmaceutical composition | 格拉斯如睦株式会社 | 2018-05-04 | — | — | CN | disclosed |
| CN-105849111-A | Pyranochromenyl phenol derivative, and pharmaceutical composition for treating metabolic syndrome or inflammatory disease | 依如睦生物科技株式会社 | 2016-08-10 | — | — | CN | disclosed |