Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 8/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Picloxydine SCHEMBL467452 | 0.82 | LMNA (0.47) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| Picloxydine SCHEMBL1705519 | 0.81 | LMNA (0.46) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL14705941 | 0.77 | SMN1; SMN2 (0.57) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL17777463 | 0.76 | LMNA (0.60) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL23035310 | 0.76 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL14705741 | 0.76 | LMNA (0.58) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL23035338 | 0.74 | LMNA (0.56) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL17356925 | 0.71 | LMNA (0.50) | LMNASMN1; SMN2NPSR1MEN1KMT2A | |
| SCHEMBL17777326 | 0.71 | KMT2A (0.49) | LMNASMN1; SMN2KMT2AMAPTALDH1A1 | |
| SCHEMBL17356957 | 0.69 | LMNA (0.62) | LMNASMN1; SMN2NPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103717597-B | Heterocyclic compounds as kinase inhibitors | 原真股份有限公司 | 2017-07-04 | — | — | CN | disclosed |
| CN-103492389-B | Pyrazolo [4,3-d] pyrimidine as inhibitors of kinases | 原真股份有限公司 | 2016-09-14 | — | — | CN | disclosed |