Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR1 | P25024 | 6/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 6/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14904772 | 1.00 | CXCR1 (0.47) | CXCR1CXCR2MAPTKMT2AKCNK3 | |
| SCHEMBL18556234 | 0.88 | MAPT (0.43) | CXCR1CXCR2MAPTKMT2AKCNK3 | |
| SCHEMBL14904771 | 0.88 | GAA (0.47) | CXCR1CXCR2MAPTKMT2AKDM4E | |
| SCHEMBL14904738 | 0.85 | MAPT (0.56) | CXCR1CXCR2MAPTKMT2AKDM4E | |
| SCHEMBL18556235 | 0.85 | MAPT (0.56) | CXCR1CXCR2MAPTKMT2AKDM4E | |
| SCHEMBL14904773 | 0.84 | CXCR1 (0.49) | CXCR1CXCR2KCNK3GAACNR1 | |
| SCHEMBL14895239 | 0.83 | SMN1; SMN2 (0.48) | CXCR1CXCR2MAPTKMT2A | |
| SCHEMBL14895238 | 0.83 | SMN1; SMN2 (0.48) | CXCR1CXCR2MAPTKMT2A | |
| SCHEMBL16144470 | 0.81 | KMT2A (0.50) | MAPTKMT2ALMNAGAA | |
| SCHEMBL7979807 | 0.77 | KMT2A (0.54) | MAPTKMT2ALMNACNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103906738-B | For treating new dibasic 3,4-diaminourea-3-cyclobutane-1,2-dione compounds of chemokine mediated disease | 高德美研究及发展公司 | 2016-09-07 | — | — | CN | disclosed |